• Version:
  • 11.0 [archived version]
STRINGSTRING
TUBGCP4 TUBGCP4 NEDD1 NEDD1 NME7 NME7 MZT1 MZT1 TUBGCP2 TUBGCP2 TUBGCP5 TUBGCP5 TUBG1 TUBG1 TUBGCP6 TUBGCP6 MZT2A MZT2A MZT2B MZT2B TUBGCP3 TUBGCP3
"MZT1" - Mitotic-spindle organizing protein 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MZT1Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome; Belongs to the MOZART1 family (82 aa)    
Predicted Functional Partners:
TUBGCP3
Gamma-tubulin complex component 3; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome (907 aa)
     
  0.999
TUBGCP6
Gamma-tubulin complex component 6; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome (1819 aa)
     
  0.999
TUBGCP4
Gamma-tubulin complex component 4; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome (667 aa)
       
  0.999
TUBG1
Tubulin gamma-1 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation; Tubulins (451 aa)
     
  0.999
MZT2B
Mitotic spindle organizing protein 2B (158 aa)
       
  0.998
TUBGCP5
Gamma-tubulin complex component 5; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome (1024 aa)
     
  0.998
MZT2A
Mitotic spindle organizing protein 2A; Belongs to the MOZART2 family (158 aa)
       
  0.997
TUBGCP2
Gamma-tubulin complex component 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome (930 aa)
       
  0.997
NME7
Nucleoside diphosphate kinase 7; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Cilia and flagella associated (376 aa)
       
  0.995
NEDD1
Protein NEDD1; Required for mitosis progression. Promotes the nucleation of microtubules from the spindle; WD repeat domain containing (667 aa)
     
  0.987
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]