• Version:
  • 11.0 [archived version]
STRINGSTRING
DNAH2 DNAH2 FAM47B FAM47B KCTD16 KCTD16 LRRC14B LRRC14B TMEM191B TMEM191B TMEM236 TMEM236 OTOGL OTOGL OR13C8 OR13C8 SHBG SHBG TTC9 TTC9 MYEOV2 MYEOV2
"TMEM236" - Transmembrane protein 236 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM236Transmembrane protein 236 (351 aa)    
Predicted Functional Partners:
TMEM191B
Transmembrane protein 191B (346 aa)
           
  0.731
OR13C8
Olfactory receptor 13C8; Odorant receptor; Olfactory receptors, family 13 (320 aa)
           
  0.723
KCTD16
BTB/POZ domain-containing protein KCTD16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity) (428 aa)
           
  0.715
SHBG
Sex hormone-binding globulin; Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration (402 aa)
       
      0.680
LRRC14B
Leucine-rich repeat-containing protein 14B; Leucine rich repeat containing 14B; Belongs to the PRAME family. LRRC14 subfamily (514 aa)
           
  0.670
TTC9
Tetratricopeptide repeat domain containing; Belongs to the TTC9 family (222 aa)
           
  0.662
OTOGL
Otogelin-like protein; Otogelin like (2344 aa)
           
  0.609
MYEOV2
Myeloma overexpressed 2 (252 aa)
           
  0.586
FAM47B
Protein FAM47B; Family with sequence similarity 47 member B; Belongs to the FAM47 family (645 aa)
           
  0.585
DNAH2
Dynein heavy chain 2, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity); Dyneins, axonemal (4427 aa)
           
  0.579
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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