• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM72C FAM72C ANKRD20A2 ANKRD20A2 ANKRD20A1 ANKRD20A1 ANKRD20A4 ANKRD20A4 CBWD7 CBWD7 CBWD1 CBWD1 CBWD2 CBWD2 RPP30 RPP30 SETD2 SETD2 TCERG1 TCERG1 KIF22 KIF22
"CBWD1" - COBW domain containing 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBWD1COBW domain containing 1 (395 aa)    
Predicted Functional Partners:
SETD2
Histone-lysine N-methyltransferase SETD2; Histone methyltransferase that specifically trimethylates ’Lys-36’ of histone H3 (H3K36me3) using dimethylated ’Lys-36’ (H3K36me2) as substrate. Represents the main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation (By similarity). Plays a role in chromatin structure modulation during elongation by coordinating recruitment of the FACT complex and by interacting with hyperphosphorylated POLR2A. Acts as a key regulator of DNA mismatch repair in G1 and early S phase by generating H3K36me3, a mark required to recr [...] (2564 aa)
     
   
  0.755
TCERG1
Transcription elongation regulator 1; Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter (1098 aa)
     
 
  0.665
KIF22
Kinesin-like protein KIF22; Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA (By similarity). Plays a role in congression of laterally attached chromosomes in NDC80- depleted cells; Kinesins (665 aa)
           
  0.635
CBWD2
COBW domain containing 2; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily (395 aa)
   
   
0.586
ANKRD20A1
Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1 (823 aa)
     
   
  0.565
ANKRD20A2
Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2 (823 aa)
     
   
  0.564
ANKRD20A4
Ankyrin repeat domain-containing protein 20A4; Ankyrin repeat domain 20 family member A4 (823 aa)
     
   
  0.564
CBWD7
COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily (395 aa)
   
 
0.554
FAM72C
Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family (149 aa)
           
  0.536
RPP30
Ribonuclease P protein subunit p30; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends (322 aa)
     
      0.530
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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