• Version:
  • 11.0 [archived version]
STRINGSTRING
PGM5 PGM5 SH3BP5L SH3BP5L PRSS3P2 PRSS3P2 IMPG2 IMPG2 TCEANC2 TCEANC2 TMEM252 TMEM252 ADCK2 ADCK2 TMX3 TMX3 PGAP3 PGAP3 CNDP1 CNDP1 NPVF NPVF
"TMEM252" - Transmembrane protein 252 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM252Transmembrane protein 252 (170 aa)    
Predicted Functional Partners:
CNDP1
Carnosine dipeptidase 1; Belongs to the peptidase M20A family (507 aa)
     
   
  0.747
ADCK2
Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (626 aa)
           
  0.718
PRSS3P2
Trypsin-2; In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family (261 aa)
       
      0.622
TCEANC2
Transcription elongation factor A N-terminal and central domain containing 2 (208 aa)
           
  0.611
TMX3
Protein disulfide-isomerase TMX3; Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase (454 aa)
           
  0.605
PGAP3
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (Probable); Belongs to the PGAP3 family (320 aa)
           
  0.574
IMPG2
Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light- sensitive photoreceptor outer segment. Binds heparin (1241 aa)
           
  0.572
SH3BP5L
SH3 binding domain protein 5 like (393 aa)
           
  0.530
NPVF
Pro-FMRFamide-related neuropeptide VF; Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine- induced analgesia; Belongs to the FARP (FMRFamide related peptide) family (196 aa)
           
  0.513
PGM5
Phosphoglucomutase-like protein 5; Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity (567 aa)
     
   
  0.458
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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