node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCK2 | IMPG2 | ENSP00000072869 | ENSP00000193391 | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light- sensitive photoreceptor outer segment. Binds heparin | 0.493 |
ADCK2 | PGAP3 | ENSP00000072869 | ENSP00000300658 | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (Probable); Belongs to the PGAP3 family | 0.557 |
ADCK2 | TMEM252 | ENSP00000072869 | ENSP00000366528 | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | Transmembrane protein 252 | 0.718 |
ADCK2 | TMX3 | ENSP00000072869 | ENSP00000299608 | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | Protein disulfide-isomerase TMX3; Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase | 0.555 |
CNDP1 | NPVF | ENSP00000351682 | ENSP00000222674 | Carnosine dipeptidase 1; Belongs to the peptidase M20A family | Pro-FMRFamide-related neuropeptide VF; Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine- induced analgesia; Belongs to the FARP (FMRFamide related peptide) family | 0.471 |
CNDP1 | TMEM252 | ENSP00000351682 | ENSP00000366528 | Carnosine dipeptidase 1; Belongs to the peptidase M20A family | Transmembrane protein 252 | 0.747 |
IMPG2 | ADCK2 | ENSP00000193391 | ENSP00000072869 | Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light- sensitive photoreceptor outer segment. Binds heparin | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | 0.493 |
IMPG2 | TMEM252 | ENSP00000193391 | ENSP00000366528 | Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light- sensitive photoreceptor outer segment. Binds heparin | Transmembrane protein 252 | 0.572 |
NPVF | CNDP1 | ENSP00000222674 | ENSP00000351682 | Pro-FMRFamide-related neuropeptide VF; Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine- induced analgesia; Belongs to the FARP (FMRFamide related peptide) family | Carnosine dipeptidase 1; Belongs to the peptidase M20A family | 0.471 |
NPVF | TMEM252 | ENSP00000222674 | ENSP00000366528 | Pro-FMRFamide-related neuropeptide VF; Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine- induced analgesia; Belongs to the FARP (FMRFamide related peptide) family | Transmembrane protein 252 | 0.513 |
PGAP3 | ADCK2 | ENSP00000300658 | ENSP00000072869 | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (Probable); Belongs to the PGAP3 family | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | 0.557 |
PGAP3 | TMEM252 | ENSP00000300658 | ENSP00000366528 | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (Probable); Belongs to the PGAP3 family | Transmembrane protein 252 | 0.574 |
PGAP3 | TMX3 | ENSP00000300658 | ENSP00000299608 | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (Probable); Belongs to the PGAP3 family | Protein disulfide-isomerase TMX3; Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase | 0.431 |
PGM5 | TMEM252 | ENSP00000379678 | ENSP00000366528 | Phosphoglucomutase-like protein 5; Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity | Transmembrane protein 252 | 0.458 |
PRSS3P2 | TMEM252 | ENSP00000485444 | ENSP00000366528 | Trypsin-2; In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family | Transmembrane protein 252 | 0.622 |
SH3BP5L | TMEM252 | ENSP00000355428 | ENSP00000366528 | SH3 binding domain protein 5 like | Transmembrane protein 252 | 0.530 |
TCEANC2 | TMEM252 | ENSP00000234827 | ENSP00000366528 | Transcription elongation factor A N-terminal and central domain containing 2 | Transmembrane protein 252 | 0.611 |
TMEM252 | ADCK2 | ENSP00000366528 | ENSP00000072869 | Transmembrane protein 252 | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | 0.718 |
TMEM252 | CNDP1 | ENSP00000366528 | ENSP00000351682 | Transmembrane protein 252 | Carnosine dipeptidase 1; Belongs to the peptidase M20A family | 0.747 |
TMEM252 | IMPG2 | ENSP00000366528 | ENSP00000193391 | Transmembrane protein 252 | Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light- sensitive photoreceptor outer segment. Binds heparin | 0.572 |