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STRINGSTRING
HMP19 HMP19 ZMAT4 ZMAT4 CCDC67 CCDC67 FCGBP FCGBP CDAN1 CDAN1 C16orf90 C16orf90 MAMDC2 MAMDC2 TK1 TK1 NCAPD3 NCAPD3 RAB21 RAB21 FNBP4 FNBP4
"MAMDC2" - MAM domain containing 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAMDC2MAM domain containing 2 (686 aa)    
Predicted Functional Partners:
NCAPD3
Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis; Armadillo-like helical domain containing (1498 aa)
            
  0.683
RAB21
Ras-related protein Rab-21; Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity); RAB, member RAS oncogene GTPases (225 aa)
            
  0.664
CDAN1
Codanin-1; May act as a negative regulator of ASF1 in chromatin assembly (1227 aa)
        
      0.622
TK1
Thymidine kinase, cytosolic; Thymidine kinase 1; Belongs to the thymidine kinase family (234 aa)
        
 
  0.529
FCGBP
Fc fragment of IgG binding protein (4204 aa)
            
  0.507
FNBP4
Formin binding protein 4 (1017 aa)
            
  0.503
HMP19
Neuronal vesicle trafficking-associated protein 2; Neuron-specific protein family member 2 (171 aa)
            
  0.493
CCDC67
Deuterosome assembly protein 1; Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity); Belongs to the CEP63 family (604 aa)
            
  0.487
ZMAT4
Zinc finger matrin-type 4 (229 aa)
            
  0.473
C16orf90
Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90 (182 aa)
            
  0.472
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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