https://version11.string-db.org/cgi/show_network_section.pl?networkId=xxVihnwMGZHr
Version:
11.0
[archived version]
Login
Register
STRING
STRING
Search
Download
Help
My Data
There are several matches for 'ENSP00000366249'.
Please select one from the list below and press Continue to proceed.
<- Back
Continue ->
organism
protein
Homo sapiens
GABBR1 - Gamma-aminobutyric acid type B receptor subunit 1; Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-depend [...]
[a.k.a. GPRC3A, Q5SUL3, ENSP00000417332,
ENSP00000366249
]
Homo sapiens
UBD - Ubiquitin D; Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear tr [...]
[a.k.a. FAT10, Ubiquitin-like protein FAT10, ENSG00000213886,
ENSP00000366249
]