• Version:
  • 11.0 [archived version]
STRINGSTRING
ANGPTL7 ANGPTL7 MASP2 MASP2 C1orf127 C1orf127 PTCHD2 PTCHD2 UBIAD1 UBIAD1 SRM SRM CCT6B CCT6B
"C1orf127" - Uncharacterized protein C1orf127 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C1orf127Uncharacterized protein C1orf127; Chromosome 1 open reading frame 127 (823 aa)    
Predicted Functional Partners:
UBIAD1
UbiA prenyltransferase domain-containing protein 1; Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform present at high concentrations in the brain, kidney and pancreas, and is required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2- methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independe [...] (338 aa)
           
  0.671
PTCHD2
Protein dispatched homolog 3; Plays a role in neuronal proliferation and differentiation. Plays a role in the accumulation of cellular cholesterol (By similarity). Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells (By similarity) (1392 aa)
           
  0.578
ANGPTL7
Angiopoietin-related protein 7; Fibrinogen C domain containing; Angiopoietin like (346 aa)
           
  0.576
CCT6B
T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins (530 aa)
       
      0.558
MASP2
Mannan-binding lectin serine protease 2; Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase; Sushi domain containing (686 aa)
           
  0.541
SRM
Spermidine synthase; Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine (302 aa)
           
  0.447
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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