WDR13 protein (human) - STRING database

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WDR13

WD repeat-containing protein 13; WD repeat domain containing (485 aa)

Predicted Functional Partners:

BBS10

0.733

AKIRIN1

0.712

JUN

0.664

GATA1

0.653

RAB44

0.634

FNDC3A

0.581

THOC2

0.560

WDR33

0.552

ZNF182

0.548

MAST4

0.547

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKIRIN1	WDR13	ENSP00000392678	ENSP00000365919	Akirin-1; Akirin 1	WD repeat-containing protein 13; WD repeat domain containing	0.712
BBS10	WDR13	ENSP00000376946	ENSP00000365919	Bardet-Biedl syndrome 10 protein; Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation; Belongs to the TCP-1 chaperonin family	WD repeat-containing protein 13; WD repeat domain containing	0.733
FNDC3A	WDR13	ENSP00000441831	ENSP00000365919	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	WD repeat-containing protein 13; WD repeat domain containing	0.581
GATA1	JUN	ENSP00000365858	ENSP00000360266	Erythroid transcription factor; Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5’-[AT]GATA[AG]-3’ within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS; GATA zinc finger domain containing	Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5’-TGA[CG]TCA-3’. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells; Basic leucine zipper proteins	0.549
GATA1	WDR13	ENSP00000365858	ENSP00000365919	Erythroid transcription factor; Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5’-[AT]GATA[AG]-3’ within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS; GATA zinc finger domain containing	WD repeat-containing protein 13; WD repeat domain containing	0.653
JUN	GATA1	ENSP00000360266	ENSP00000365858	Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5’-TGA[CG]TCA-3’. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells; Basic leucine zipper proteins	Erythroid transcription factor; Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5’-[AT]GATA[AG]-3’ within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS; GATA zinc finger domain containing	0.549
JUN	WDR13	ENSP00000360266	ENSP00000365919	Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5’-TGA[CG]TCA-3’. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells; Basic leucine zipper proteins	WD repeat-containing protein 13; WD repeat domain containing	0.664
MAST4	WDR13	ENSP00000385727	ENSP00000365919	Microtubule associated serine/threonine kinase family member 4; PDZ domain containing	WD repeat-containing protein 13; WD repeat domain containing	0.547
RAB44	WDR13	ENSP00000481054	ENSP00000365919	Ras-related protein Rab-44; RAB44, member RAS oncogene family	WD repeat-containing protein 13; WD repeat domain containing	0.634
THOC2	WDR13	ENSP00000245838	ENSP00000365919	THO complex subunit 2; Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cyt [...]	WD repeat-containing protein 13; WD repeat domain containing	0.560
THOC2	WDR33	ENSP00000245838	ENSP00000325377	THO complex subunit 2; Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cyt [...]	pre-mRNA 3’ end processing protein WDR33; Essential for both cleavage and polyadenylation of pre- mRNA 3’ ends; WD repeat domain containing	0.909
WDR13	AKIRIN1	ENSP00000365919	ENSP00000392678	WD repeat-containing protein 13; WD repeat domain containing	Akirin-1; Akirin 1	0.712
WDR13	BBS10	ENSP00000365919	ENSP00000376946	WD repeat-containing protein 13; WD repeat domain containing	Bardet-Biedl syndrome 10 protein; Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation; Belongs to the TCP-1 chaperonin family	0.733
WDR13	FNDC3A	ENSP00000365919	ENSP00000441831	WD repeat-containing protein 13; WD repeat domain containing	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	0.581
WDR13	GATA1	ENSP00000365919	ENSP00000365858	WD repeat-containing protein 13; WD repeat domain containing	Erythroid transcription factor; Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5’-[AT]GATA[AG]-3’ within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS; GATA zinc finger domain containing	0.653
WDR13	JUN	ENSP00000365919	ENSP00000360266	WD repeat-containing protein 13; WD repeat domain containing	Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5’-TGA[CG]TCA-3’. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells; Basic leucine zipper proteins	0.664
WDR13	MAST4	ENSP00000365919	ENSP00000385727	WD repeat-containing protein 13; WD repeat domain containing	Microtubule associated serine/threonine kinase family member 4; PDZ domain containing	0.547
WDR13	RAB44	ENSP00000365919	ENSP00000481054	WD repeat-containing protein 13; WD repeat domain containing	Ras-related protein Rab-44; RAB44, member RAS oncogene family	0.634
WDR13	THOC2	ENSP00000365919	ENSP00000245838	WD repeat-containing protein 13; WD repeat domain containing	THO complex subunit 2; Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cyt [...]	0.560
WDR13	WDR33	ENSP00000365919	ENSP00000325377	WD repeat-containing protein 13; WD repeat domain containing	pre-mRNA 3’ end processing protein WDR33; Essential for both cleavage and polyadenylation of pre- mRNA 3’ ends; WD repeat domain containing	0.552

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