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  • 11.0 [archived version]
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NUDT22 NUDT22 NUDT5 NUDT5 NUDT12 NUDT12 PMPCA PMPCA NUDT8 NUDT8 PMPCB PMPCB UQCRC1 UQCRC1 RPL36A RPL36A RPL36AL RPL36AL FAM174B FAM174B QARS QARS
"NUDT8" - Nucleoside diphosphate-linked moiety X motif 8 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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NUDT8Nucleoside diphosphate-linked moiety X motif 8; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Nudix hydrolase family (236 aa)    
Predicted Functional Partners:
PMPCA
Mitochondrial-processing peptidase subunit alpha; Cleaves presequences (transit peptides) from mitochondrial protein precursors; Belongs to the peptidase M16 family (525 aa)
     
      0.910
FAM174B
Membrane protein FAM174B; Family with sequence similarity 174 member B (159 aa)
           
  0.762
UQCRC1
Cytochrome b-c1 complex subunit 1, mitochondrial; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1; M16 metallopeptidases (480 aa)
     
      0.739
PMPCB
Mitochondrial-processing peptidase subunit beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors; M16 metallopeptidases (489 aa)
     
      0.732
QARS
Glutamine--tRNA ligase; Glutamine--tRNA ligase. Plays a critical role in brain development; Belongs to the class-I aminoacyl-tRNA synthetase family (775 aa)
   
 
  0.723
NUDT5
ADP-sugar pyrophosphatase; Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate. In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5- phosphate. Nuclear ATP synthesis takes place [...] (219 aa)
           
  0.697
NUDT22
Nucleoside diphosphate-linked moiety X motif 22; Nudix hydrolase family (303 aa)
           
  0.694
RPL36AL
Ribosomal protein L36a like (106 aa)
       
 
  0.690
RPL36A
Ribosomal protein L36a (142 aa)
       
 
  0.689
NUDT12
Peroxisomal NADH pyrophosphatase NUDT12; Hydrolyzes NAD(P)H to NMNH and AMP (2’,5’-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle; Belongs to the Nudix hydrolase family. NudC subfamily (462 aa)
   
   
  0.686
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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