node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CELA3A | CPA1 | ENSP00000290122 | ENSP00000011292 | Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | 0.969 |
CELA3A | CPA2 | ENSP00000290122 | ENSP00000222481 | Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity | M14 carboxypeptidases | 0.831 |
CELA3A | CPB1 | ENSP00000290122 | ENSP00000417222 | Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity | M14 carboxypeptidases; Belongs to the peptidase M14 family | 0.877 |
CELA3A | CPB2 | ENSP00000290122 | ENSP00000181383 | Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity | Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin; Belongs to the peptidase M14 family | 0.425 |
CELA3A | CTRC | ENSP00000290122 | ENSP00000365116 | Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity | Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity | 0.779 |
CELA3A | PRSS1 | ENSP00000290122 | ENSP00000308720 | Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity | Trypsin-1; Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates; Belongs to the peptidase S1 family | 0.494 |
CELA3B | CPA1 | ENSP00000338369 | ENSP00000011292 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | 0.979 |
CELA3B | CPA2 | ENSP00000338369 | ENSP00000222481 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity | M14 carboxypeptidases | 0.690 |
CELA3B | CPB1 | ENSP00000338369 | ENSP00000417222 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity | M14 carboxypeptidases; Belongs to the peptidase M14 family | 0.913 |
CELA3B | CPB2 | ENSP00000338369 | ENSP00000181383 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity | Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin; Belongs to the peptidase M14 family | 0.485 |
CELA3B | CTRC | ENSP00000338369 | ENSP00000365116 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity | Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity | 0.819 |
CELA3B | SPINK1 | ENSP00000338369 | ENSP00000296695 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens (By similarity); Serine peptidase inhibitors, Kazal type | 0.614 |
CPA1 | CELA3A | ENSP00000011292 | ENSP00000290122 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity | 0.969 |
CPA1 | CELA3B | ENSP00000011292 | ENSP00000338369 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity | 0.979 |
CPA1 | CPA2 | ENSP00000011292 | ENSP00000222481 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | M14 carboxypeptidases | 0.867 |
CPA1 | CPB1 | ENSP00000011292 | ENSP00000417222 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | M14 carboxypeptidases; Belongs to the peptidase M14 family | 0.844 |
CPA1 | CTRC | ENSP00000011292 | ENSP00000365116 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity | 0.952 |
CPA1 | PRSS1 | ENSP00000011292 | ENSP00000308720 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | Trypsin-1; Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates; Belongs to the peptidase S1 family | 0.778 |
CPA1 | SPINK1 | ENSP00000011292 | ENSP00000296695 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens (By similarity); Serine peptidase inhibitors, Kazal type | 0.685 |
CPA2 | CELA3A | ENSP00000222481 | ENSP00000290122 | M14 carboxypeptidases | Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity | 0.831 |