• Version:
  • 11.0 [archived version]
STRINGSTRING
TRIM40 TRIM40 LY6G5C LY6G5C LY6G5B LY6G5B ABHD16A ABHD16A GPANK1 GPANK1 FGFR3 FGFR3 C6orf47 C6orf47 PRRC2A PRRC2A ZBTB12 ZBTB12 TSC22D4 TSC22D4 POLR2J POLR2J
"C6orf47" - Uncharacterized protein C6orf47 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C6orf47Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47 (294 aa)    
Predicted Functional Partners:
TSC22D4
TSC22 domain family protein 4; Transcriptional repressor (395 aa)
           
  0.714
GPANK1
G-patch domain and ankyrin repeats 1 (356 aa)
     
   
  0.670
LY6G5C
Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation; LY6/PLAUR domain containing (150 aa)
           
  0.647
PRRC2A
Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing (2157 aa)
           
  0.567
POLR2J
DNA-directed RNA polymerase II subunit RPB11-a; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity) (117 aa)
           
  0.562
ZBTB12
Zinc finger and BTB domain-containing protein 12; May be involved in transcriptional regulation; BTB domain containing (459 aa)
           
  0.558
ABHD16A
Protein ABHD16A; Abhydrolase domain containing 16A (558 aa)
           
  0.557
FGFR3
Fibroblast growth factor receptor 3; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear. Ph [...] (808 aa)
       
      0.552
TRIM40
Tripartite motif-containing protein 40; May function as an E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway. Promotes neddylation of IKBKG/NEMO, stabilizing NFKBIA, and inhibiting of NF-kappaB nuclear translocation and activity; Belongs to the TRIM/RBCC family (258 aa)
           
  0.530
LY6G5B
Lymphocyte antigen 6 family member G5B; LY6/PLAUR domain containing (201 aa)
           
  0.529
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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