GPANK1 protein (human) - STRING database

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Score

GPANK1

G-patch domain and ankyrin repeats 1 (356 aa)

Predicted Functional Partners:

APOM

0.931

ABHD16A

0.883

ZBTB12

0.804

PRRC2A

0.794

C6orf47

0.670

SFXN5

0.653

B3GAT2

0.646

CNPY3

0.629

RARS2

0.628

ASCC3

0.609

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD16A	C6orf47	ENSP00000379282	ENSP00000365076	Protein ABHD16A; Abhydrolase domain containing 16A	Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47	0.557
ABHD16A	GPANK1	ENSP00000379282	ENSP00000365071	Protein ABHD16A; Abhydrolase domain containing 16A	G-patch domain and ankyrin repeats 1	0.883
ABHD16A	PRRC2A	ENSP00000379282	ENSP00000365201	Protein ABHD16A; Abhydrolase domain containing 16A	Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing	0.748
ABHD16A	ZBTB12	ENSP00000379282	ENSP00000364677	Protein ABHD16A; Abhydrolase domain containing 16A	Zinc finger and BTB domain-containing protein 12; May be involved in transcriptional regulation; BTB domain containing	0.755
APOM	C6orf47	ENSP00000365081	ENSP00000365076	Apolipoprotein M; Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid; Apolipoproteins	Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47	0.485
APOM	GPANK1	ENSP00000365081	ENSP00000365071	Apolipoprotein M; Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid; Apolipoproteins	G-patch domain and ankyrin repeats 1	0.931
ASCC3	B3GAT2	ENSP00000358159	ENSP00000230053	Activating signal cointegrator 1 complex subunit 3; 3’-5’ DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation; Belongs to the helicase family	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins; Beta-1,3-glucuronyltransferases	0.636
ASCC3	CNPY3	ENSP00000358159	ENSP00000361926	Activating signal cointegrator 1 complex subunit 3; 3’-5’ DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation; Belongs to the helicase family	Protein canopy homolog 3; Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity); Belongs to the canopy family	0.675
ASCC3	GPANK1	ENSP00000358159	ENSP00000365071	Activating signal cointegrator 1 complex subunit 3; 3’-5’ DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation; Belongs to the helicase family	G-patch domain and ankyrin repeats 1	0.609
ASCC3	PRRC2A	ENSP00000358159	ENSP00000365201	Activating signal cointegrator 1 complex subunit 3; 3’-5’ DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation; Belongs to the helicase family	Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing	0.566
ASCC3	RARS2	ENSP00000358159	ENSP00000358549	Activating signal cointegrator 1 complex subunit 3; 3’-5’ DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation; Belongs to the helicase family	Probable arginine--tRNA ligase, mitochondrial; arginyl-tRNA synthetase 2, mitochondrial; Aminoacyl tRNA synthetases, Class I	0.652
ASCC3	SFXN5	ENSP00000358159	ENSP00000272433	Activating signal cointegrator 1 complex subunit 3; 3’-5’ DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation; Belongs to the helicase family	Sideroflexin-5; Transports citrate. Potential iron transporter (By similarity); Sideroflexins	0.711
B3GAT2	ASCC3	ENSP00000230053	ENSP00000358159	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins; Beta-1,3-glucuronyltransferases	Activating signal cointegrator 1 complex subunit 3; 3’-5’ DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation; Belongs to the helicase family	0.636
B3GAT2	CNPY3	ENSP00000230053	ENSP00000361926	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins; Beta-1,3-glucuronyltransferases	Protein canopy homolog 3; Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity); Belongs to the canopy family	0.644
B3GAT2	GPANK1	ENSP00000230053	ENSP00000365071	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins; Beta-1,3-glucuronyltransferases	G-patch domain and ankyrin repeats 1	0.646
B3GAT2	PRRC2A	ENSP00000230053	ENSP00000365201	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins; Beta-1,3-glucuronyltransferases	Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing	0.527
B3GAT2	RARS2	ENSP00000230053	ENSP00000358549	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins; Beta-1,3-glucuronyltransferases	Probable arginine--tRNA ligase, mitochondrial; arginyl-tRNA synthetase 2, mitochondrial; Aminoacyl tRNA synthetases, Class I	0.554
B3GAT2	SFXN5	ENSP00000230053	ENSP00000272433	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins; Beta-1,3-glucuronyltransferases	Sideroflexin-5; Transports citrate. Potential iron transporter (By similarity); Sideroflexins	0.683
C6orf47	ABHD16A	ENSP00000365076	ENSP00000379282	Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47	Protein ABHD16A; Abhydrolase domain containing 16A	0.557
C6orf47	APOM	ENSP00000365076	ENSP00000365081	Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47	Apolipoprotein M; Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid; Apolipoproteins	0.485

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