SECISBP2 protein (human) - STRING database

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SECISBP2

Selenocysteine insertion sequence-binding protein 2; Binds to the SECIS element in the 3’-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB (854 aa)

Predicted Functional Partners:

EEFSEC

0.997

RPL30

0.979

RPL7A

0.961

RPS13

0.909

RPS25

0.909

RPS21

0.908

RPL14

0.908

RPL12

0.906

RPS12

0.902

RPL10

0.900

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEFSEC	RPL10	ENSP00000254730	ENSP00000413436	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	0.937
EEFSEC	RPL12	ENSP00000254730	ENSP00000354739	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	60S ribosomal protein L12; Binds directly to 26S ribosomal RNA	0.948
EEFSEC	RPL14	ENSP00000254730	ENSP00000379506	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	60S ribosomal protein L14; Component of the large ribosomal subunit; Belongs to the eukaryotic ribosomal protein eL14 family	0.912
EEFSEC	RPL30	ENSP00000254730	ENSP00000428085	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	0.980
EEFSEC	RPL7A	ENSP00000254730	ENSP00000361076	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein L7a	0.967
EEFSEC	RPS12	ENSP00000254730	ENSP00000230050	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein S12	0.943
EEFSEC	RPS13	ENSP00000254730	ENSP00000435777	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein S13	0.948
EEFSEC	RPS21	ENSP00000254730	ENSP00000345957	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family	0.908
EEFSEC	RPS25	ENSP00000254730	ENSP00000435096	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Ribosomal protein S25	0.965
EEFSEC	SECISBP2	ENSP00000254730	ENSP00000364965	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	Selenocysteine insertion sequence-binding protein 2; Binds to the SECIS element in the 3’-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB	0.997
RPL10	EEFSEC	ENSP00000413436	ENSP00000254730	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP	0.937
RPL10	RPL12	ENSP00000413436	ENSP00000354739	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	60S ribosomal protein L12; Binds directly to 26S ribosomal RNA	0.999
RPL10	RPL14	ENSP00000413436	ENSP00000379506	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	60S ribosomal protein L14; Component of the large ribosomal subunit; Belongs to the eukaryotic ribosomal protein eL14 family	0.999
RPL10	RPL30	ENSP00000413436	ENSP00000428085	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family	0.999
RPL10	RPL7A	ENSP00000413436	ENSP00000361076	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	Ribosomal protein L7a	0.999
RPL10	RPS12	ENSP00000413436	ENSP00000230050	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	Ribosomal protein S12	0.999
RPL10	RPS13	ENSP00000413436	ENSP00000435777	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	Ribosomal protein S13	0.999
RPL10	RPS21	ENSP00000413436	ENSP00000345957	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	Ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family	0.999
RPL10	RPS25	ENSP00000413436	ENSP00000435096	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	Ribosomal protein S25	0.999
RPL10	SECISBP2	ENSP00000413436	ENSP00000364965	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development	Selenocysteine insertion sequence-binding protein 2; Binds to the SECIS element in the 3’-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB	0.900

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