node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD16A | GPANK1 | ENSP00000379282 | ENSP00000365071 | Protein ABHD16A; Abhydrolase domain containing 16A | G-patch domain and ankyrin repeats 1 | 0.883 |
ABHD16A | PRRC2A | ENSP00000379282 | ENSP00000365201 | Protein ABHD16A; Abhydrolase domain containing 16A | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | 0.748 |
ABHD16A | VARS | ENSP00000379282 | ENSP00000364815 | Protein ABHD16A; Abhydrolase domain containing 16A | Valine--tRNA ligase; Aminoacyl tRNA synthetases, Class I | 0.484 |
ABHD16A | ZBTB12 | ENSP00000379282 | ENSP00000364677 | Protein ABHD16A; Abhydrolase domain containing 16A | Zinc finger and BTB domain-containing protein 12; May be involved in transcriptional regulation; BTB domain containing | 0.755 |
CTNNBL1 | ZBTB12 | ENSP00000355050 | ENSP00000364677 | Beta-catenin-like protein 1; Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis; Armadillo-like helical domain containing | Zinc finger and BTB domain-containing protein 12; May be involved in transcriptional regulation; BTB domain containing | 0.764 |
DDAH1 | PRRC2A | ENSP00000284031 | ENSP00000365201 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | 0.559 |
DDAH1 | PRRT1 | ENSP00000284031 | ENSP00000211413 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation | Interferon induced transmembrane protein domain containing; Belongs to the CD225/Dispanin family | 0.472 |
DDAH1 | SKIV2L | ENSP00000284031 | ENSP00000364543 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation | Helicase SKI2W; Helicase; has ATPase activity. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C); Belongs to the helicase family. SKI2 subfamily | 0.641 |
DDAH1 | ZBTB12 | ENSP00000284031 | ENSP00000364677 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation | Zinc finger and BTB domain-containing protein 12; May be involved in transcriptional regulation; BTB domain containing | 0.663 |
EHMT2 | GPANK1 | ENSP00000364678 | ENSP00000365071 | Histone-lysine N-methyltransferase EHMT2; Histone methyltransferase that specifically mono- and dimethylates ’Lys-9’ of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of ’Lys-56’ of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates ’Lys-27’ of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltr [...] | G-patch domain and ankyrin repeats 1 | 0.514 |
EHMT2 | PRRC2A | ENSP00000364678 | ENSP00000365201 | Histone-lysine N-methyltransferase EHMT2; Histone methyltransferase that specifically mono- and dimethylates ’Lys-9’ of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of ’Lys-56’ of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates ’Lys-27’ of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltr [...] | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | 0.516 |
EHMT2 | ZBTB12 | ENSP00000364678 | ENSP00000364677 | Histone-lysine N-methyltransferase EHMT2; Histone methyltransferase that specifically mono- and dimethylates ’Lys-9’ of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of ’Lys-56’ of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates ’Lys-27’ of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltr [...] | Zinc finger and BTB domain-containing protein 12; May be involved in transcriptional regulation; BTB domain containing | 0.603 |
GPANK1 | ABHD16A | ENSP00000365071 | ENSP00000379282 | G-patch domain and ankyrin repeats 1 | Protein ABHD16A; Abhydrolase domain containing 16A | 0.883 |
GPANK1 | EHMT2 | ENSP00000365071 | ENSP00000364678 | G-patch domain and ankyrin repeats 1 | Histone-lysine N-methyltransferase EHMT2; Histone methyltransferase that specifically mono- and dimethylates ’Lys-9’ of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of ’Lys-56’ of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates ’Lys-27’ of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltr [...] | 0.514 |
GPANK1 | PRRC2A | ENSP00000365071 | ENSP00000365201 | G-patch domain and ankyrin repeats 1 | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | 0.794 |
GPANK1 | ZBTB12 | ENSP00000365071 | ENSP00000364677 | G-patch domain and ankyrin repeats 1 | Zinc finger and BTB domain-containing protein 12; May be involved in transcriptional regulation; BTB domain containing | 0.804 |
PRRC2A | ABHD16A | ENSP00000365201 | ENSP00000379282 | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | Protein ABHD16A; Abhydrolase domain containing 16A | 0.748 |
PRRC2A | DDAH1 | ENSP00000365201 | ENSP00000284031 | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation | 0.559 |
PRRC2A | EHMT2 | ENSP00000365201 | ENSP00000364678 | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | Histone-lysine N-methyltransferase EHMT2; Histone methyltransferase that specifically mono- and dimethylates ’Lys-9’ of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of ’Lys-56’ of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates ’Lys-27’ of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltr [...] | 0.516 |
PRRC2A | GPANK1 | ENSP00000365201 | ENSP00000365071 | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | G-patch domain and ankyrin repeats 1 | 0.794 |