LYZL1 protein (human) - STRING database

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LYZL1

Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family (194 aa)

Predicted Functional Partners:

PRSS55

0.661

CCDC73

0.595

TEX37

0.585

CCDC42

0.583

KIAA1462

0.525

ASTL

0.491

DEFB118

0.480

NXT2

0.474

KATNAL1

0.467

SGK494

0.467

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASTL	LYZL1	ENSP00000343674	ENSP00000364650	Astacin-like metalloendopeptidase; Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity); Belongs to the peptidase M12A family	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	0.491
CCDC42	CCDC73	ENSP00000293845	ENSP00000335325	Coiled-coil domain-containing protein 42; Required for sperm development	Coiled-coil domain containing 73	0.632
CCDC42	LYZL1	ENSP00000293845	ENSP00000364650	Coiled-coil domain-containing protein 42; Required for sperm development	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	0.583
CCDC42	NXT2	ENSP00000293845	ENSP00000218004	Coiled-coil domain-containing protein 42; Required for sperm development	NTF2-related export protein 2; Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export	0.528
CCDC42	PRSS55	ENSP00000293845	ENSP00000333003	Coiled-coil domain-containing protein 42; Required for sperm development	Serine protease 55; Probable serine protease	0.466
CCDC42	TEX37	ENSP00000293845	ENSP00000307142	Coiled-coil domain-containing protein 42; Required for sperm development	Testis-expressed sequence 37 protein; Testis expressed 37	0.591
CCDC73	CCDC42	ENSP00000335325	ENSP00000293845	Coiled-coil domain containing 73	Coiled-coil domain-containing protein 42; Required for sperm development	0.632
CCDC73	LYZL1	ENSP00000335325	ENSP00000364650	Coiled-coil domain containing 73	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	0.595
CCDC73	NXT2	ENSP00000335325	ENSP00000218004	Coiled-coil domain containing 73	NTF2-related export protein 2; Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export	0.521
CCDC73	PRSS55	ENSP00000335325	ENSP00000333003	Coiled-coil domain containing 73	Serine protease 55; Probable serine protease	0.703
CCDC73	TEX37	ENSP00000335325	ENSP00000307142	Coiled-coil domain containing 73	Testis-expressed sequence 37 protein; Testis expressed 37	0.608
DEFB118	LYZL1	ENSP00000253381	ENSP00000364650	Beta-defensin 118; Has antibacterial activity; Defensins, beta	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	0.480
KATNAL1	LYZL1	ENSP00000369989	ENSP00000364650	Katanin p60 ATPase-containing subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro; Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	0.467
KIAA1462	LYZL1	ENSP00000364526	ENSP00000364650	Junctional protein associated with coronary artery disease; KIAA1462	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	0.525
LYZL1	ASTL	ENSP00000364650	ENSP00000343674	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	Astacin-like metalloendopeptidase; Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity); Belongs to the peptidase M12A family	0.491
LYZL1	CCDC42	ENSP00000364650	ENSP00000293845	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	Coiled-coil domain-containing protein 42; Required for sperm development	0.583
LYZL1	CCDC73	ENSP00000364650	ENSP00000335325	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	Coiled-coil domain containing 73	0.595
LYZL1	DEFB118	ENSP00000364650	ENSP00000253381	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	Beta-defensin 118; Has antibacterial activity; Defensins, beta	0.480
LYZL1	KATNAL1	ENSP00000364650	ENSP00000369989	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	Katanin p60 ATPase-containing subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro; Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily	0.467
LYZL1	KIAA1462	ENSP00000364650	ENSP00000364526	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	Junctional protein associated with coronary artery disease; KIAA1462	0.525

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