node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACIN1 | C9orf129 | ENSP00000262710 | ENSP00000364568 | Apoptotic chromatin condensation inducer in the nucleus; Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP complexes which bind RNA in a sequence- independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate [...] | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | 0.429 |
ASTN2 | C9orf129 | ENSP00000354504 | ENSP00000364568 | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5- trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6); Fibronectin type III domain containing | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | 0.489 |
ASTN2 | KIAA1328 | ENSP00000354504 | ENSP00000280020 | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5- trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6); Fibronectin type III domain containing | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | 0.626 |
BCL9L | C9orf129 | ENSP00000335320 | ENSP00000364568 | B-cell CLL/lymphoma 9-like protein; Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity); Belongs to the BCL9 family | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | 0.473 |
BRWD1 | C9orf129 | ENSP00000330753 | ENSP00000364568 | Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | 0.533 |
C9orf129 | ACIN1 | ENSP00000364568 | ENSP00000262710 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | Apoptotic chromatin condensation inducer in the nucleus; Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP complexes which bind RNA in a sequence- independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate [...] | 0.429 |
C9orf129 | ASTN2 | ENSP00000364568 | ENSP00000354504 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5- trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6); Fibronectin type III domain containing | 0.489 |
C9orf129 | BCL9L | ENSP00000364568 | ENSP00000335320 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | B-cell CLL/lymphoma 9-like protein; Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity); Belongs to the BCL9 family | 0.473 |
C9orf129 | BRWD1 | ENSP00000364568 | ENSP00000330753 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing | 0.533 |
C9orf129 | FAF1 | ENSP00000364568 | ENSP00000379457 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | FAS-associated factor 1; Potentiates but cannot initiate FAS-induced apoptosis; UBX domain containing | 0.452 |
C9orf129 | KIAA1328 | ENSP00000364568 | ENSP00000280020 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | 0.669 |
C9orf129 | LRRIQ1 | ENSP00000364568 | ENSP00000376910 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | Leucine rich repeats and IQ motif containing 1 | 0.644 |
C9orf129 | PEAK1 | ENSP00000364568 | ENSP00000452796 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | Pseudopodium-enriched atypical kinase 1; Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN | 0.530 |
C9orf129 | SEC14L1 | ENSP00000364568 | ENSP00000376268 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | SEC14-like protein 1; May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters; PRELI domain containing | 0.557 |
C9orf129 | ZNF704 | ENSP00000364568 | ENSP00000331462 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | Zinc finger protein 704 | 0.426 |
FAF1 | C9orf129 | ENSP00000379457 | ENSP00000364568 | FAS-associated factor 1; Potentiates but cannot initiate FAS-induced apoptosis; UBX domain containing | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | 0.452 |
KIAA1328 | ASTN2 | ENSP00000280020 | ENSP00000354504 | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5- trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6); Fibronectin type III domain containing | 0.626 |
KIAA1328 | C9orf129 | ENSP00000280020 | ENSP00000364568 | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | 0.669 |
KIAA1328 | LRRIQ1 | ENSP00000280020 | ENSP00000376910 | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | Leucine rich repeats and IQ motif containing 1 | 0.416 |
LRRIQ1 | C9orf129 | ENSP00000376910 | ENSP00000364568 | Leucine rich repeats and IQ motif containing 1 | Putative uncharacterized protein C9orf129; Chromosome 9 open reading frame 129 | 0.644 |