node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADPRHL1 | C2CD2 | ENSP00000364567 | ENSP00000369853 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | C2 calcium dependent domain containing 2 | 0.718 |
ADPRHL1 | DGAT2 | ENSP00000364567 | ENSP00000228027 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | Diacylglycerol O-acyltransferase 2; Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT); Diacylglycerol O-acyltransferase 2 family | 0.584 |
ADPRHL1 | GPATCH8 | ENSP00000364567 | ENSP00000467556 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | G-patch domain containing 8 | 0.582 |
ADPRHL1 | GPRIN1 | ENSP00000364567 | ENSP00000305839 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | 0.512 |
ADPRHL1 | GRTP1 | ENSP00000364567 | ENSP00000364579 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s) | 0.547 |
ADPRHL1 | NOL9 | ENSP00000364567 | ENSP00000366934 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | Polynucleotide 5’-hydroxyl-kinase NOL9; Polynucleotide 5’-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5’-kinase activities. Probably binds RNA; Belongs to the Clp1 family. NOL9/GRC3 subfamily | 0.561 |
ADPRHL1 | PCGF1 | ENSP00000364567 | ENSP00000233630 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | Polycomb group RING finger protein 1; Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin- dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell [...] | 0.515 |
ADPRHL1 | RBBP8NL | ENSP00000364567 | ENSP00000252998 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | RBBP8 N-terminal-like protein; RBBP8 N-terminal like | 0.681 |
ADPRHL1 | TRIM27 | ENSP00000364567 | ENSP00000366404 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | Zinc finger protein RFP; E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity; mediates the formation of ’Lys-48’-linked polyubiquitin chains; the function inhibits CD4 T- cell activation. Acts as a regulator of retrograde transport- together with MAGEL2, mediates the formation of ’Lys-63’-linked polyubiquitin chains at ’Lys-220’ of WASHC1, leading to promote endosomal F-actin assembly. Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspas [...] | 0.513 |
ADPRHL1 | WDTC1 | ENSP00000364567 | ENSP00000317971 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | WD and tetratricopeptide repeats protein 1; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | 0.532 |
C2CD2 | ADPRHL1 | ENSP00000369853 | ENSP00000364567 | C2 calcium dependent domain containing 2 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | 0.718 |
C2CD2 | NOL9 | ENSP00000369853 | ENSP00000366934 | C2 calcium dependent domain containing 2 | Polynucleotide 5’-hydroxyl-kinase NOL9; Polynucleotide 5’-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5’-kinase activities. Probably binds RNA; Belongs to the Clp1 family. NOL9/GRC3 subfamily | 0.705 |
C2CD2 | RBBP8NL | ENSP00000369853 | ENSP00000252998 | C2 calcium dependent domain containing 2 | RBBP8 N-terminal-like protein; RBBP8 N-terminal like | 0.753 |
DGAT2 | ADPRHL1 | ENSP00000228027 | ENSP00000364567 | Diacylglycerol O-acyltransferase 2; Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT); Diacylglycerol O-acyltransferase 2 family | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | 0.584 |
GPATCH8 | ADPRHL1 | ENSP00000467556 | ENSP00000364567 | G-patch domain containing 8 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | 0.582 |
GPATCH8 | GPRIN1 | ENSP00000467556 | ENSP00000305839 | G-patch domain containing 8 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | 0.597 |
GPRIN1 | ADPRHL1 | ENSP00000305839 | ENSP00000364567 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | 0.512 |
GPRIN1 | GPATCH8 | ENSP00000305839 | ENSP00000467556 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | G-patch domain containing 8 | 0.597 |
GRTP1 | ADPRHL1 | ENSP00000364579 | ENSP00000364567 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s) | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | 0.547 |
NOL9 | ADPRHL1 | ENSP00000366934 | ENSP00000364567 | Polynucleotide 5’-hydroxyl-kinase NOL9; Polynucleotide 5’-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5’-kinase activities. Probably binds RNA; Belongs to the Clp1 family. NOL9/GRC3 subfamily | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 | 0.561 |