• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM213A FAM213A ANKRD16 ANKRD16 SMYD1 SMYD1 FBXL17 FBXL17 MRPS27 MRPS27 AAED1 AAED1 AADACL2 AADACL2 ZNF367 ZNF367 UBOX5 UBOX5 AADACL3 AADACL3 RNF122 RNF122
"AAED1" - Thioredoxin-like protein AAED1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AAED1Thioredoxin-like protein AAED1; AhpC/TSA antioxidant enzyme domain containing 1; Belongs to the AAED1 family (226 aa)    
Predicted Functional Partners:
ZNF367
Zinc finger protein 367; Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes; Zinc fingers C2H2-type (350 aa)
       
 
  0.832
FBXL17
F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins (701 aa)
           
  0.782
MRPS27
28S ribosomal protein S27, mitochondrial; RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth (428 aa)
           
  0.768
UBOX5
RING finger protein 37; May have a ubiquitin-protein ligase activity acting as an E3 ubiquitin-protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates; Ring finger proteins (541 aa)
     
   
  0.758
RNF122
RING finger protein 122; May induce necrosis and apoptosis. May play a role in cell viability; Ring finger proteins (155 aa)
     
   
  0.621
AADACL3
Arylacetamide deacetylase-like 3; Arylacetamide deacetylase family (350 aa)
           
  0.570
SMYD1
Histone-lysine N-methyltransferase SMYD1; Methylates histone H3 at ’Lys-4’ (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis; Belongs to the class V-like SAM-binding methyltransferase superfamily (490 aa)
     
   
  0.555
FAM213A
Redox-regulatory protein FAM213A; Involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway; Belongs to the peroxiredoxin-like FAM213 family. FAM213A subfamily (229 aa)
     
   
  0.555
ANKRD16
Ankyrin repeat domain-containing protein 16; Ankyrin repeat domain containing (361 aa)
     
   
  0.543
AADACL2
Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family (401 aa)
           
  0.537
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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