| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AP3B1 | ZXDB | ENSP00000255194 | ENSP00000364023 | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.528 |
| CCDC144NL | CCDC180 | ENSP00000328054 | ENSP00000434727 | Putative coiled-coil domain-containing protein 144 N-terminal-like; Coiled-coil domain containing 144 family, N-terminal like; Belongs to the CCDC144 family | Coiled-coil domain containing 180 | 0.668 |
| CCDC144NL | ZXDB | ENSP00000328054 | ENSP00000364023 | Putative coiled-coil domain-containing protein 144 N-terminal-like; Coiled-coil domain containing 144 family, N-terminal like; Belongs to the CCDC144 family | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.669 |
| CCDC180 | CCDC144NL | ENSP00000434727 | ENSP00000328054 | Coiled-coil domain containing 180 | Putative coiled-coil domain-containing protein 144 N-terminal-like; Coiled-coil domain containing 144 family, N-terminal like; Belongs to the CCDC144 family | 0.668 |
| CCDC180 | ZXDB | ENSP00000434727 | ENSP00000364023 | Coiled-coil domain containing 180 | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.473 |
| DPY19L3 | MANEAL | ENSP00000344937 | ENSP00000362136 | Probable C-mannosyltransferase DPY19L3; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins; Belongs to the dpy-19 family | Glycoprotein endo-alpha-1,2-mannosidase-like protein; Mannosidase endo-alpha like; Belongs to the glycosyl hydrolase 99 family | 0.481 |
| DPY19L3 | ZXDB | ENSP00000344937 | ENSP00000364023 | Probable C-mannosyltransferase DPY19L3; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins; Belongs to the dpy-19 family | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.503 |
| FRAT2 | ZXDB | ENSP00000360058 | ENSP00000364023 | GSK-3-binding protein FRAT2; Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3 | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.476 |
| MANEAL | DPY19L3 | ENSP00000362136 | ENSP00000344937 | Glycoprotein endo-alpha-1,2-mannosidase-like protein; Mannosidase endo-alpha like; Belongs to the glycosyl hydrolase 99 family | Probable C-mannosyltransferase DPY19L3; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins; Belongs to the dpy-19 family | 0.481 |
| MANEAL | ZXDB | ENSP00000362136 | ENSP00000364023 | Glycoprotein endo-alpha-1,2-mannosidase-like protein; Mannosidase endo-alpha like; Belongs to the glycosyl hydrolase 99 family | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.473 |
| NSUN3 | ZXDB | ENSP00000318986 | ENSP00000364023 | tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial; Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt-tRNA(Met). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5-formylcytosine (f(5)c) at this position. mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation; Belongs to the class I-like SAM-bindin [...] | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.652 |
| PAPD5 | ZXDB | ENSP00000396995 | ENSP00000364023 | Non-canonical poly(A) RNA polymerase PAPD5; Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn’t need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion; Belongs to the [...] | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.506 |
| SLITRK2 | TMEM164 | ENSP00000359521 | ENSP00000361143 | SLIT and NTRK-like protein 2; It is involved in synaptogenesis and promotes excitatory synapse differentiation. Suppresses neurite outgrowth (By similarity) | Transmembrane protein 164; Belongs to the TMEM164 family | 0.680 |
| SLITRK2 | ZXDB | ENSP00000359521 | ENSP00000364023 | SLIT and NTRK-like protein 2; It is involved in synaptogenesis and promotes excitatory synapse differentiation. Suppresses neurite outgrowth (By similarity) | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.584 |
| TMEM164 | SLITRK2 | ENSP00000361143 | ENSP00000359521 | Transmembrane protein 164; Belongs to the TMEM164 family | SLIT and NTRK-like protein 2; It is involved in synaptogenesis and promotes excitatory synapse differentiation. Suppresses neurite outgrowth (By similarity) | 0.680 |
| TMEM164 | ZXDB | ENSP00000361143 | ENSP00000364023 | Transmembrane protein 164; Belongs to the TMEM164 family | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | 0.696 |
| ZXDB | AP3B1 | ENSP00000364023 | ENSP00000255194 | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | 0.528 |
| ZXDB | CCDC144NL | ENSP00000364023 | ENSP00000328054 | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | Putative coiled-coil domain-containing protein 144 N-terminal-like; Coiled-coil domain containing 144 family, N-terminal like; Belongs to the CCDC144 family | 0.669 |
| ZXDB | CCDC180 | ENSP00000364023 | ENSP00000434727 | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | Coiled-coil domain containing 180 | 0.473 |
| ZXDB | DPY19L3 | ENSP00000364023 | ENSP00000344937 | Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Belongs to the ZXD family | Probable C-mannosyltransferase DPY19L3; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins; Belongs to the dpy-19 family | 0.503 |
