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  • 11.0 [archived version]
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SLC35E4 SLC35E4 SLC36A2 SLC36A2 RBMS3 RBMS3 FAM73B FAM73B NPEPL1 NPEPL1 SHISA4 SHISA4 SLC38A10 SLC38A10 TMEM105 TMEM105 SLC36A1 SLC36A1 ENTHD2 ENTHD2 SLC38A9 SLC38A9
"SLC38A10" - Putative sodium-coupled neutral amino acid transporter 10 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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SLC38A10Putative sodium-coupled neutral amino acid transporter 10; Putative sodium-dependent amino acid/proton antiporter; Solute carriers (1119 aa)    
Predicted Functional Partners:
TMEM105
Transmembrane protein 105 (129 aa)
     
   
  0.683
NPEPL1
Probable aminopeptidase NPEPL1; Probably catalyzes the removal of unsubstituted N- terminal amino acids from various peptides; Aminopeptidases (523 aa)
     
   
  0.649
SLC38A9
Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino a [...] (561 aa)
           
  0.639
ENTHD2
AP-4 complex accessory subunit Tepsin; Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network (525 aa)
 
 
   
  0.628
SHISA4
Protein shisa-4; Shisa family member 4 (197 aa)
           
  0.596
SLC35E4
Solute carrier family 35 member E4; Putative transporter; Solute carriers (350 aa)
     
   
  0.591
SLC36A1
Proton-coupled amino acid transporter 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity); Solute carriers (476 aa)
     
 
  0.583
SLC36A2
Proton-coupled amino acid transporter 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity); Belongs to the amino acid/polyamine transporter 2 family (483 aa)
     
 
  0.562
RBMS3
RNA-binding motif, single-stranded-interacting protein 3; Binds poly(A) and poly(U) oligoribonucleotides; RNA binding motif containing (437 aa)
           
  0.537
FAM73B
Mitoguardin 2; Regulator of mitochondrial fusion- acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family (593 aa)
     
   
  0.517
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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