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  • 11.0 [archived version]
STRINGSTRING
CTNNAL1 CTNNAL1 C16orf97 C16orf97 KIAA1751 KIAA1751 CCIN CCIN ACTL7B ACTL7B CAPZA3 CAPZA3 IKBKAP IKBKAP UBQLNL UBQLNL SSSCA1 SSSCA1 PDHA2 PDHA2 PGK2 PGK2
"ACTL7B" - Actin-like protein 7B in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ACTL7BActin-like protein 7B; Actin related proteins; Belongs to the actin family (415 aa)    
Predicted Functional Partners:
CTNNAL1
Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) (734 aa)
        
 
  0.796
IKBKAP
Elongator complex protein 1; May act as a scaffold protein that may assemble active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK); Belongs to the ELP1/IKA1 family (1332 aa)
            
  0.715
C16orf97
Uncharacterized protein C16orf97; Chromosome 16 open reading frame 97 (126 aa)
            
  0.644
SSSCA1
Sjoegren syndrome/scleroderma autoantigen 1; Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies (199 aa)
            
  0.582
KIAA1751
Cilia- and flagella-associated protein 74; As part of the central apparatus of the cilium axoneme may play a role in cilium movement (1584 aa)
            
  0.571
PDHA2
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle (388 aa)
      
   
  0.570
CCIN
Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing (588 aa)
      
 
  0.562
CAPZA3
F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) (299 aa)
      
 
  0.549
UBQLNL
Ubiquilin-like protein; Ubiquilin family (475 aa)
      
 
  0.534
PGK2
Phosphoglycerate kinase 2; Essential for sperm motility and male fertility. Not required for the completion of spermatogenesis (By similarity); Belongs to the phosphoglycerate kinase family (417 aa)
      
 
  0.509
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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