| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C12orf45 | TMEM245 | ENSP00000447057 | ENSP00000363714 | Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45 | Transmembrane protein 245 | 0.528 |
| C2CD2L | TMEM245 | ENSP00000338885 | ENSP00000363714 | Phospholipid transfer protein C2CD2L; Lipid-binding protein that transports phosphatidylinositol, the precursor of phosphatidylinositol 4,5- bisphosphate (PI(4,5)P2), from its site of synthesis in the endoplasmic reticulum to the cell membrane. It thereby maintains the pool of cell membrane phosphoinositides, which are degraded during phospholipase C (PLC) signaling. Plays a key role in the coordination of Ca(2+) and phosphoinositide signaling- localizes to sites of contact between the endoplasmic reticulum and the cell membrane, where it tethers the two bilayers. In response to elevat [...] | Transmembrane protein 245 | 0.458 |
| CTNNAL1 | DCAF10 | ENSP00000320434 | ENSP00000366953 | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) | DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | 0.406 |
| CTNNAL1 | FAM166B | ENSP00000320434 | ENSP00000382646 | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) | Protein FAM166B; Family with sequence similarity 166 member B | 0.413 |
| CTNNAL1 | TMEM245 | ENSP00000320434 | ENSP00000363714 | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) | Transmembrane protein 245 | 0.778 |
| DCAF10 | CTNNAL1 | ENSP00000366953 | ENSP00000320434 | DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) | 0.406 |
| DCAF10 | FAM166B | ENSP00000366953 | ENSP00000382646 | DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | Protein FAM166B; Family with sequence similarity 166 member B | 0.556 |
| DCAF10 | TMEM245 | ENSP00000366953 | ENSP00000363714 | DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | Transmembrane protein 245 | 0.475 |
| FAM166B | CTNNAL1 | ENSP00000382646 | ENSP00000320434 | Protein FAM166B; Family with sequence similarity 166 member B | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) | 0.413 |
| FAM166B | DCAF10 | ENSP00000382646 | ENSP00000366953 | Protein FAM166B; Family with sequence similarity 166 member B | DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | 0.556 |
| FAM166B | TMEM245 | ENSP00000382646 | ENSP00000363714 | Protein FAM166B; Family with sequence similarity 166 member B | Transmembrane protein 245 | 0.480 |
| FNDC3B | TMEM245 | ENSP00000338523 | ENSP00000363714 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | Transmembrane protein 245 | 0.499 |
| SASS6 | TMEM245 | ENSP00000287482 | ENSP00000363714 | Spindle assembly abnormal protein 6 homolog; Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication- required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers. Required for the recruitment of STIL to the procentriole and for STIL-mediated centriole amplification | Transmembrane protein 245 | 0.640 |
| SRA1 | TMEM245 | ENSP00000337513 | ENSP00000363714 | Steroid receptor RNA activator 1; Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis; Belongs to the SRA1 family | Transmembrane protein 245 | 0.554 |
| SUSD1 | TMEM245 | ENSP00000363382 | ENSP00000363714 | Sushi domain containing 1 | Transmembrane protein 245 | 0.527 |
| SUSD1 | ZNF483 | ENSP00000363382 | ENSP00000311679 | Sushi domain containing 1 | Zinc finger protein 483; May be involved in transcriptional regulation; SCAN domain containing | 0.604 |
| TMEM245 | C12orf45 | ENSP00000363714 | ENSP00000447057 | Transmembrane protein 245 | Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45 | 0.528 |
| TMEM245 | C2CD2L | ENSP00000363714 | ENSP00000338885 | Transmembrane protein 245 | Phospholipid transfer protein C2CD2L; Lipid-binding protein that transports phosphatidylinositol, the precursor of phosphatidylinositol 4,5- bisphosphate (PI(4,5)P2), from its site of synthesis in the endoplasmic reticulum to the cell membrane. It thereby maintains the pool of cell membrane phosphoinositides, which are degraded during phospholipase C (PLC) signaling. Plays a key role in the coordination of Ca(2+) and phosphoinositide signaling- localizes to sites of contact between the endoplasmic reticulum and the cell membrane, where it tethers the two bilayers. In response to elevat [...] | 0.458 |
| TMEM245 | CTNNAL1 | ENSP00000363714 | ENSP00000320434 | Transmembrane protein 245 | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) | 0.778 |
| TMEM245 | DCAF10 | ENSP00000363714 | ENSP00000366953 | Transmembrane protein 245 | DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | 0.475 |
