• Version:
  • 11.0 [archived version]
STRINGSTRING
MFAP3L MFAP3L AKAP1 AKAP1 MTURN MTURN ZNF704 ZNF704 SH3BGRL2 SH3BGRL2 PPP1R11 PPP1R11 MTFR1L MTFR1L EXPH5 EXPH5 NET1 NET1 ARHGEF9 ARHGEF9 CDC42EP1 CDC42EP1
"MTFR1L" - Mitochondrial fission regulator 1 like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTFR1LMitochondrial fission regulator 1 like; Belongs to the MTFR1 family (292 aa)    
Predicted Functional Partners:
ZNF704
Zinc finger protein 704 (412 aa)
           
  0.511
MTURN
Maturin; May be involved in early neuronal development (131 aa)
           
  0.502
MFAP3L
Microfibrillar-associated protein 3-like; May participate in the nuclear signaling of EGFR and MAPK1/ERK2. May a have a role in metastasis; I-set domain containing (409 aa)
           
  0.497
SH3BGRL2
SH3 domain binding glutamate rich protein like 2; Belongs to the SH3BGR family (107 aa)
           
  0.450
ARHGEF9
Rho guanine nucleotide exchange factor 9; Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters; Pleckstrin homology domain containing (516 aa)
           
  0.449
NET1
Neuroepithelial cell-transforming gene 1 protein; Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death; Pleckstrin homology domain containing (596 aa)
           
  0.440
CDC42EP1
Cdc42 effector protein 1; Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts; CDC42 effector proteins (391 aa)
           
  0.429
PPP1R11
Protein phosphatase 1 regulatory subunit 11; Inhibitor of protein phosphatase 1; Cilia and flagella associated (126 aa)
           
  0.424
EXPH5
Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking (1989 aa)
           
  0.420
AKAP1
A-kinase anchor protein 1, mitochondrial; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane; A-kinase anchoring proteins (903 aa)
           
  0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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