• Version:
  • 11.0 [archived version]
STRINGSTRING
MMRN2 MMRN2 FAM25HP FAM25HP FAM25A FAM25A ZPLD1 ZPLD1 THUMPD2 THUMPD2 AGAP5 AGAP5 TATDN1 TATDN1 KATNBL1 KATNBL1 HDHD3 HDHD3 C1orf115 C1orf115 TMEM220 TMEM220
"AGAP5" - Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
AGAP5Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5; Putative GTPase-activating protein; Ankyrin repeat domain containing (686 aa)    
Predicted Functional Partners:
FAM25A
Family with sequence similarity 25 member A; Belongs to the FAM25 family (89 aa)
           
  0.653
FAM25HP
Protein FAM25A; Family with sequence similarity 25, member H pseudogene; Belongs to the FAM25 family (89 aa)
           
  0.571
TMEM220
Transmembrane protein 220 (160 aa)
           
  0.548
MMRN2
Multimerin-2; Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA; EMI domain containing (949 aa)
           
  0.541
THUMPD2
THUMP domain-containing protein 2; Seven-beta-strand methyltransferase motif containing; Belongs to the methyltransferase superfamily (503 aa)
           
  0.530
HDHD3
Haloacid dehalogenase like hydrolase domain containing 3 (251 aa)
           
  0.519
C1orf115
Uncharacterized protein C1orf115; Chromosome 1 open reading frame 115 (142 aa)
           
  0.512
KATNBL1
KATNB1-like protein 1; Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro (304 aa)
           
  0.479
TATDN1
Putative deoxyribonuclease TATDN1; Putative deoxyribonuclease; Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family (297 aa)
           
  0.478
ZPLD1
Zona pellucida-like domain-containing protein 1; Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ (431 aa)
           
  0.474
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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