MEGF9 protein (human) - STRING database

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MEGF9

Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9 (602 aa)

Predicted Functional Partners:

CCNJ

0.732

DLK2

0.678

EGFL6

0.677

ENPEP

0.604

FAM208A

0.583

TIGD2

0.583

STX11

0.576

NPNT

0.575

EGF

0.544

EGFL8

0.539

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNJ	ENPEP	ENSP00000435373	ENSP00000265162	Cyclin-J; Cyclin J; Cyclins	Glutamyl aminopeptidase; Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells; Belongs to the peptidase M1 family	0.513
CCNJ	MEGF9	ENSP00000435373	ENSP00000363040	Cyclin-J; Cyclin J; Cyclins	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	0.732
DLK2	EGFL8	ENSP00000349893	ENSP00000378888	Protein delta homolog 2; Regulates adipogenesis	Epidermal growth factor-like protein 8; EGF like domain multiple 8	0.517
DLK2	MEGF9	ENSP00000349893	ENSP00000363040	Protein delta homolog 2; Regulates adipogenesis	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	0.678
EGF	EGFL8	ENSP00000265171	ENSP00000378888	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro	Epidermal growth factor-like protein 8; EGF like domain multiple 8	0.534
EGF	MEGF9	ENSP00000265171	ENSP00000363040	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	0.544
EGFL6	MEGF9	ENSP00000369976	ENSP00000363040	Epidermal growth factor-like protein 6; May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity); Belongs to the nephronectin family	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	0.677
EGFL8	DLK2	ENSP00000378888	ENSP00000349893	Epidermal growth factor-like protein 8; EGF like domain multiple 8	Protein delta homolog 2; Regulates adipogenesis	0.517
EGFL8	EGF	ENSP00000378888	ENSP00000265171	Epidermal growth factor-like protein 8; EGF like domain multiple 8	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro	0.534
EGFL8	MEGF9	ENSP00000378888	ENSP00000363040	Epidermal growth factor-like protein 8; EGF like domain multiple 8	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	0.539
EGFL8	NPNT	ENSP00000378888	ENSP00000389252	Epidermal growth factor-like protein 8; EGF like domain multiple 8	Nephronectin; Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha- 8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins (By similarity)	0.665
ENPEP	CCNJ	ENSP00000265162	ENSP00000435373	Glutamyl aminopeptidase; Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells; Belongs to the peptidase M1 family	Cyclin-J; Cyclin J; Cyclins	0.513
ENPEP	MEGF9	ENSP00000265162	ENSP00000363040	Glutamyl aminopeptidase; Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells; Belongs to the peptidase M1 family	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	0.604
FAM208A	MEGF9	ENSP00000417509	ENSP00000363040	Protein TASOR; Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3; Belongs to the FAM208 family	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	0.583
MEGF9	CCNJ	ENSP00000363040	ENSP00000435373	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	Cyclin-J; Cyclin J; Cyclins	0.732
MEGF9	DLK2	ENSP00000363040	ENSP00000349893	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	Protein delta homolog 2; Regulates adipogenesis	0.678
MEGF9	EGF	ENSP00000363040	ENSP00000265171	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro	0.544
MEGF9	EGFL6	ENSP00000363040	ENSP00000369976	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	Epidermal growth factor-like protein 6; May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity); Belongs to the nephronectin family	0.677
MEGF9	EGFL8	ENSP00000363040	ENSP00000378888	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	Epidermal growth factor-like protein 8; EGF like domain multiple 8	0.539
MEGF9	ENPEP	ENSP00000363040	ENSP00000265162	Multiple epidermal growth factor-like domains protein 9; Multiple EGF like domains 9	Glutamyl aminopeptidase; Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells; Belongs to the peptidase M1 family	0.604

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