node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AADAT | ARMC4 | ENSP00000423190 | ENSP00000306410 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing | 0.530 |
AADAT | IQCE | ENSP00000423190 | ENSP00000480715 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling | 0.500 |
AADAT | NT5C3A | ENSP00000423190 | ENSP00000484415 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) | Cytosolic 5’-nucleotidase 3A; Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP). CMP seems to be the preferred substrate; Belongs to the pyrimidine 5’-nucleotidase family | 0.454 |
AADAT | PHYHIPL | ENSP00000423190 | ENSP00000362987 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system; Fibronectin type III domain containing | 0.507 |
AADAT | TMEM143 | ENSP00000423190 | ENSP00000293261 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) | Transmembrane protein 143 | 0.474 |
AADAT | TMEM186 | ENSP00000423190 | ENSP00000331640 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) | Transmembrane protein 186 | 0.582 |
ARMC4 | AADAT | ENSP00000306410 | ENSP00000423190 | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) | 0.530 |
ARMC4 | IQCE | ENSP00000306410 | ENSP00000480715 | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling | 0.660 |
ARMC4 | MYL10 | ENSP00000306410 | ENSP00000223167 | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing | Myosin regulatory light chain 10; EF-hand domain containing | 0.571 |
ARMC4 | NT5C3A | ENSP00000306410 | ENSP00000484415 | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing | Cytosolic 5’-nucleotidase 3A; Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP). CMP seems to be the preferred substrate; Belongs to the pyrimidine 5’-nucleotidase family | 0.517 |
ARMC4 | PHYHIPL | ENSP00000306410 | ENSP00000362987 | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system; Fibronectin type III domain containing | 0.589 |
ARMC4 | TMEM143 | ENSP00000306410 | ENSP00000293261 | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing | Transmembrane protein 143 | 0.741 |
ARMC4 | TMEM186 | ENSP00000306410 | ENSP00000331640 | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing | Transmembrane protein 186 | 0.748 |
CCSER1 | PHYHIPL | ENSP00000425040 | ENSP00000362987 | Coiled-coil serine rich protein 1 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system; Fibronectin type III domain containing | 0.537 |
IQCE | AADAT | ENSP00000480715 | ENSP00000423190 | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) | 0.500 |
IQCE | ARMC4 | ENSP00000480715 | ENSP00000306410 | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing | 0.660 |
IQCE | MYL10 | ENSP00000480715 | ENSP00000223167 | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling | Myosin regulatory light chain 10; EF-hand domain containing | 0.513 |
IQCE | NT5C3A | ENSP00000480715 | ENSP00000484415 | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling | Cytosolic 5’-nucleotidase 3A; Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP). CMP seems to be the preferred substrate; Belongs to the pyrimidine 5’-nucleotidase family | 0.538 |
IQCE | PHYHIPL | ENSP00000480715 | ENSP00000362987 | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system; Fibronectin type III domain containing | 0.695 |
IQCE | TMEM143 | ENSP00000480715 | ENSP00000293261 | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling | Transmembrane protein 143 | 0.670 |