• Version:
  • 11.0 [archived version]
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CCSER1 CCSER1 PSD2 PSD2 AADAT AADAT PHYHIPL PHYHIPL ARMC4 ARMC4 MYL10 MYL10 IQCE IQCE UMPS UMPS TMEM186 TMEM186 NT5C3A NT5C3A TMEM143 TMEM143
"PHYHIPL" - Phytanoyl-CoA hydroxylase-interacting protein-like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
PHYHIPLPhytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system; Fibronectin type III domain containing (376 aa)    
Predicted Functional Partners:
TMEM186
Transmembrane protein 186 (213 aa)
           
  0.743
IQCE
IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (702 aa)
           
  0.695
NT5C3A
Cytosolic 5’-nucleotidase 3A; Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP). CMP seems to be the preferred substrate; Belongs to the pyrimidine 5’-nucleotidase family (336 aa)
           
  0.605
TMEM143
Transmembrane protein 143 (459 aa)
           
  0.595
ARMC4
Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly; Armadillo repeat containing (1044 aa)
     
   
  0.589
PSD2
Pleckstrin and Sec7 domain containing 2 (771 aa)
     
   
  0.544
CCSER1
Coiled-coil serine rich protein 1 (900 aa)
           
  0.537
MYL10
Myosin regulatory light chain 10; EF-hand domain containing (226 aa)
           
  0.531
AADAT
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) (429 aa)
           
  0.507
UMPS
Uridine 5’-monophosphate synthase; Uridine monophosphate synthetase; In the C-terminal section; belongs to the OMP decarboxylase family (480 aa)
           
  0.505
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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