| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP6V0A1 | SERINC2 | ENSP00000264649 | ENSP00000362814 | V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity); V-type ATPases | Serine incorporator 2; Belongs to the TDE1 family | 0.554 |
| GPRC5C | SERINC2 | ENSP00000376403 | ENSP00000362814 | G-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways; G protein-coupled receptors, Class C orphans | Serine incorporator 2; Belongs to the TDE1 family | 0.690 |
| GPRC5C | STARD10 | ENSP00000376403 | ENSP00000335247 | G-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways; G protein-coupled receptors, Class C orphans | START domain-containing protein 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | 0.530 |
| IPO11 | KIAA0040 | ENSP00000386992 | ENSP00000464040 | Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis r [...] | Uncharacterized protein KIAA0040; KIAA0040 | 0.495 |
| IPO11 | NKAIN1 | ENSP00000386992 | ENSP00000362841 | Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis r [...] | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | 0.426 |
| IPO11 | PHF3 | ENSP00000386992 | ENSP00000262043 | Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis r [...] | PHD finger protein 3 | 0.558 |
| IPO11 | SERINC2 | ENSP00000386992 | ENSP00000362814 | Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis r [...] | Serine incorporator 2; Belongs to the TDE1 family | 0.575 |
| KIAA0040 | IPO11 | ENSP00000464040 | ENSP00000386992 | Uncharacterized protein KIAA0040; KIAA0040 | Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis r [...] | 0.495 |
| KIAA0040 | PHF3 | ENSP00000464040 | ENSP00000262043 | Uncharacterized protein KIAA0040; KIAA0040 | PHD finger protein 3 | 0.473 |
| KIAA0040 | SERINC2 | ENSP00000464040 | ENSP00000362814 | Uncharacterized protein KIAA0040; KIAA0040 | Serine incorporator 2; Belongs to the TDE1 family | 0.668 |
| LAPTM5 | SERINC2 | ENSP00000294507 | ENSP00000362814 | Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells; Belongs to the LAPTM4/LAPTM5 transporter family | Serine incorporator 2; Belongs to the TDE1 family | 0.601 |
| NKAIN1 | IPO11 | ENSP00000362841 | ENSP00000386992 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis r [...] | 0.426 |
| NKAIN1 | PHF3 | ENSP00000362841 | ENSP00000262043 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | PHD finger protein 3 | 0.437 |
| NKAIN1 | SERINC2 | ENSP00000362841 | ENSP00000362814 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | Serine incorporator 2; Belongs to the TDE1 family | 0.626 |
| NKAIN1 | ZCCHC17 | ENSP00000362841 | ENSP00000480986 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | Nucleolar protein of 40 kDa; Zinc finger CCHC-type containing 17 | 0.691 |
| PHF3 | IPO11 | ENSP00000262043 | ENSP00000386992 | PHD finger protein 3 | Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis r [...] | 0.558 |
| PHF3 | KIAA0040 | ENSP00000262043 | ENSP00000464040 | PHD finger protein 3 | Uncharacterized protein KIAA0040; KIAA0040 | 0.473 |
| PHF3 | NKAIN1 | ENSP00000262043 | ENSP00000362841 | PHD finger protein 3 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | 0.437 |
| PHF3 | SERINC2 | ENSP00000262043 | ENSP00000362814 | PHD finger protein 3 | Serine incorporator 2; Belongs to the TDE1 family | 0.535 |
| PUM1 | SERINC2 | ENSP00000391723 | ENSP00000362814 | Pumilio homolog 1; Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3’-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5’-UGUANAUA-3’, that is related to the Nanos Response Element (NRE). Mediates post-transcriptional repression of transcripts via different mechanisms- acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation. Also mediates deadenylation-independent repression by promoting accessibility of miRNAs. Following growth fa [...] | Serine incorporator 2; Belongs to the TDE1 family | 0.561 |
