| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACTA1 | CCIN | ENSP00000355645 | ENSP00000334996 | Actin, alpha skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | 0.410 |
| ACTA1 | ZBTB6 | ENSP00000355645 | ENSP00000362763 | Actin, alpha skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | Zinc finger and BTB domain-containing protein 6; May be involved in transcriptional regulation; BTB domain containing | 0.762 |
| AGL | ZBTB6 | ENSP00000294724 | ENSP00000362763 | Glycogen debranching enzyme; Multifunctional enzyme acting as 1,4-alpha-D-glucan-1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6- glucosidase in glycogen degradation; Belongs to the glycogen debranching enzyme family | Zinc finger and BTB domain-containing protein 6; May be involved in transcriptional regulation; BTB domain containing | 0.629 |
| ANKFY1 | BTBD7 | ENSP00000459943 | ENSP00000335615 | Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosyn [...] | BTB/POZ domain-containing protein 7; Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity); BTB domain containing | 0.412 |
| ANKFY1 | CCIN | ENSP00000459943 | ENSP00000334996 | Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosyn [...] | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | 0.410 |
| ANKFY1 | KCTD2 | ENSP00000459943 | ENSP00000312814 | Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosyn [...] | BTB/POZ domain-containing protein KCTD2; Potassium channel tetramerization domain containing 2 | 0.508 |
| ANKFY1 | ZBTB6 | ENSP00000459943 | ENSP00000362763 | Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosyn [...] | Zinc finger and BTB domain-containing protein 6; May be involved in transcriptional regulation; BTB domain containing | 0.575 |
| BTBD7 | ANKFY1 | ENSP00000335615 | ENSP00000459943 | BTB/POZ domain-containing protein 7; Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity); BTB domain containing | Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosyn [...] | 0.412 |
| BTBD7 | CCIN | ENSP00000335615 | ENSP00000334996 | BTB/POZ domain-containing protein 7; Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity); BTB domain containing | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | 0.502 |
| BTBD7 | KCTD2 | ENSP00000335615 | ENSP00000312814 | BTB/POZ domain-containing protein 7; Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity); BTB domain containing | BTB/POZ domain-containing protein KCTD2; Potassium channel tetramerization domain containing 2 | 0.507 |
| BTBD7 | KLHL18 | ENSP00000335615 | ENSP00000232766 | BTB/POZ domain-containing protein 7; Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity); BTB domain containing | Kelch-like protein 18; Kelch like family member 18; BTB domain containing | 0.537 |
| BTBD7 | ZBTB26 | ENSP00000335615 | ENSP00000362760 | BTB/POZ domain-containing protein 7; Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity); BTB domain containing | Zinc finger and BTB domain-containing protein 26; May be involved in transcriptional regulation; BTB domain containing | 0.421 |
| BTBD7 | ZBTB6 | ENSP00000335615 | ENSP00000362763 | BTB/POZ domain-containing protein 7; Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity); BTB domain containing | Zinc finger and BTB domain-containing protein 6; May be involved in transcriptional regulation; BTB domain containing | 0.629 |
| CCIN | ACTA1 | ENSP00000334996 | ENSP00000355645 | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | Actin, alpha skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | 0.410 |
| CCIN | ANKFY1 | ENSP00000334996 | ENSP00000459943 | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosyn [...] | 0.410 |
| CCIN | BTBD7 | ENSP00000334996 | ENSP00000335615 | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | BTB/POZ domain-containing protein 7; Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity); BTB domain containing | 0.502 |
| CCIN | KCTD2 | ENSP00000334996 | ENSP00000312814 | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | BTB/POZ domain-containing protein KCTD2; Potassium channel tetramerization domain containing 2 | 0.519 |
| CCIN | ZBTB6 | ENSP00000334996 | ENSP00000362763 | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | Zinc finger and BTB domain-containing protein 6; May be involved in transcriptional regulation; BTB domain containing | 0.667 |
| CYGB | ZBTB6 | ENSP00000293230 | ENSP00000362763 | Cytoglobin; May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer | Zinc finger and BTB domain-containing protein 6; May be involved in transcriptional regulation; BTB domain containing | 0.583 |
| KCTD2 | ANKFY1 | ENSP00000312814 | ENSP00000459943 | BTB/POZ domain-containing protein KCTD2; Potassium channel tetramerization domain containing 2 | Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosyn [...] | 0.508 |
