node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAI2 | DOCK1 | ENSP00000362759 | ENSP00000280333 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | 0.539 |
BAI2 | GPR137C | ENSP00000362759 | ENSP00000315106 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Integral membrane protein GPR137C; G protein-coupled receptor 137C | 0.581 |
BAI2 | KCNJ4 | ENSP00000362759 | ENSP00000306497 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Inward rectifier potassium channel 4; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity); Potassium voltage-gated channel subfamily J | 0.525 |
BAI2 | MAGI1 | ENSP00000362759 | ENSP00000385450 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity); Membrane associated guanylate kinases | 0.651 |
BAI2 | RHOJ | ENSP00000362759 | ENSP00000316729 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Rho-related GTP-binding protein RhoJ; GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology (By similarity); Rho family GTPases | 0.540 |
BAI2 | RLF | ENSP00000362759 | ENSP00000361857 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Zinc finger protein Rlf; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.545 |
BAI2 | TMEM132E | ENSP00000362759 | ENSP00000316532 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Transmembrane protein 132E; Required for normal inner ear hair cell function and hearing; Belongs to the TMEM132 family | 0.577 |
BAI2 | TMEM211 | ENSP00000362759 | ENSP00000385494 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Transmembrane protein 211 | 0.570 |
BAI2 | TMEM212 | ENSP00000362759 | ENSP00000334072 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Transmembrane protein 212 | 0.573 |
BAI2 | TMEM221 | ENSP00000362759 | ENSP00000342162 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | Transmembrane protein 221 | 0.553 |
DOCK1 | BAI2 | ENSP00000280333 | ENSP00000362759 | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | 0.539 |
DOCK1 | MAGI1 | ENSP00000280333 | ENSP00000385450 | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity); Membrane associated guanylate kinases | 0.419 |
DOCK1 | RHOJ | ENSP00000280333 | ENSP00000316729 | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | Rho-related GTP-binding protein RhoJ; GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology (By similarity); Rho family GTPases | 0.598 |
GPR137C | BAI2 | ENSP00000315106 | ENSP00000362759 | Integral membrane protein GPR137C; G protein-coupled receptor 137C | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | 0.581 |
GPR137C | TMEM132E | ENSP00000315106 | ENSP00000316532 | Integral membrane protein GPR137C; G protein-coupled receptor 137C | Transmembrane protein 132E; Required for normal inner ear hair cell function and hearing; Belongs to the TMEM132 family | 0.629 |
GPR137C | TMEM211 | ENSP00000315106 | ENSP00000385494 | Integral membrane protein GPR137C; G protein-coupled receptor 137C | Transmembrane protein 211 | 0.630 |
GPR137C | TMEM212 | ENSP00000315106 | ENSP00000334072 | Integral membrane protein GPR137C; G protein-coupled receptor 137C | Transmembrane protein 212 | 0.633 |
GPR137C | TMEM221 | ENSP00000315106 | ENSP00000342162 | Integral membrane protein GPR137C; G protein-coupled receptor 137C | Transmembrane protein 221 | 0.646 |
KCNJ4 | BAI2 | ENSP00000306497 | ENSP00000362759 | Inward rectifier potassium channel 4; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity); Potassium voltage-gated channel subfamily J | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | 0.525 |
MAGI1 | BAI2 | ENSP00000385450 | ENSP00000362759 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity); Membrane associated guanylate kinases | Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition (By similarity) | 0.651 |