• Version:
  • 11.0 [archived version]
STRINGSTRING
TSSK3 TSSK3 OR52B4 OR52B4 CCDC28B CCDC28B YEATS2 YEATS2 SLC22A14 SLC22A14 ZBTB8A ZBTB8A PNMA5 PNMA5 OR2AT4 OR2AT4 RPL9 RPL9 KCNQ5 KCNQ5 S100PBP S100PBP
"ZBTB8A" - Zinc finger and BTB domain-containing protein 8A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB8AZinc finger and BTB domain-containing protein 8A; May be involved in transcriptional regulation; BTB domain containing (441 aa)    
Predicted Functional Partners:
RPL9
L ribosomal proteins (192 aa)
        
      0.650
CCDC28B
Coiled-coil domain-containing protein 28B; Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex (241 aa)
            
  0.559
SLC22A14
Solute carrier family 22 member 14; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family (594 aa)
            
  0.546
PNMA5
Paraneoplastic antigen-like protein 5; Paraneoplastic Ma antigens; Belongs to the PNMA family (448 aa)
        
      0.540
OR52B4
Olfactory receptor 52B4; Odorant receptor; Olfactory receptors, family 52 (314 aa)
            
  0.525
OR2AT4
Olfactory receptor 2AT4; Odorant receptor; Olfactory receptors, family 2 (320 aa)
            
  0.524
TSSK3
Testis-specific serine/threonine-protein kinase 3; May be involved in a signaling pathway during male germ cell development or mature sperm function (268 aa)
      
 
  0.482
YEATS2
YEATS domain-containing protein 2; Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at ’Lys-27’ (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (1422 aa)
            
  0.479
KCNQ5
Potassium voltage-gated channel subfamily KQT member 5; Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. Therefore, it is important in the regulation of neuronal excitability. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M- channels, varying in kinetic and pharmacological properties, which underlie this physiologically important curren [...] (951 aa)
        
 
  0.470
S100PBP
S100P binding protein (408 aa)
            
  0.468
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >