node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BTBD8 | TMEM54 | ENSP00000343686 | ENSP00000362562 | BTB/POZ domain-containing protein 8; BTB domain containing 8 | Transmembrane protein 54 | 0.473 |
RARS2 | TMEM54 | ENSP00000358549 | ENSP00000362562 | Probable arginine--tRNA ligase, mitochondrial; arginyl-tRNA synthetase 2, mitochondrial; Aminoacyl tRNA synthetases, Class I | Transmembrane protein 54 | 0.531 |
RARS2 | TSEN2 | ENSP00000358549 | ENSP00000284995 | Probable arginine--tRNA ligase, mitochondrial; arginyl-tRNA synthetase 2, mitochondrial; Aminoacyl tRNA synthetases, Class I | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’- and 3’-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’-cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] | 0.865 |
RARS2 | TSEN34 | ENSP00000358549 | ENSP00000397402 | Probable arginine--tRNA ligase, mitochondrial; arginyl-tRNA synthetase 2, mitochondrial; Aminoacyl tRNA synthetases, Class I | tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’- and 3’-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’-cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] | 0.870 |
RARS2 | TSEN54 | ENSP00000358549 | ENSP00000327487 | Probable arginine--tRNA ligase, mitochondrial; arginyl-tRNA synthetase 2, mitochondrial; Aminoacyl tRNA synthetases, Class I | tRNA-splicing endonuclease subunit Sen54; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’ and 3’ splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’ cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA bo [...] | 0.870 |
STAC3 | TMEM54 | ENSP00000329200 | ENSP00000362562 | SH3 and cysteine-rich domain-containing protein 3; In skeletal muscles contraction, may play a role in neuromuscular synaptic transmission | Transmembrane protein 54 | 0.589 |
TMEM101 | TMEM177 | ENSP00000468025 | ENSP00000402661 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways | Transmembrane protein 177 | 0.562 |
TMEM101 | TMEM208 | ENSP00000468025 | ENSP00000305892 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways | Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy | 0.525 |
TMEM101 | TMEM54 | ENSP00000468025 | ENSP00000362562 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways | Transmembrane protein 54 | 0.483 |
TMEM101 | ZNF205 | ENSP00000468025 | ENSP00000480401 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways | Zinc finger protein 205; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.485 |
TMEM177 | TMEM101 | ENSP00000402661 | ENSP00000468025 | Transmembrane protein 177 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways | 0.562 |
TMEM177 | TMEM208 | ENSP00000402661 | ENSP00000305892 | Transmembrane protein 177 | Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy | 0.561 |
TMEM177 | TMEM54 | ENSP00000402661 | ENSP00000362562 | Transmembrane protein 177 | Transmembrane protein 54 | 0.523 |
TMEM177 | ZNF205 | ENSP00000402661 | ENSP00000480401 | Transmembrane protein 177 | Zinc finger protein 205; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.520 |
TMEM208 | TMEM101 | ENSP00000305892 | ENSP00000468025 | Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy | Transmembrane protein 101; May activate NF-kappa-B signaling pathways | 0.525 |
TMEM208 | TMEM177 | ENSP00000305892 | ENSP00000402661 | Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy | Transmembrane protein 177 | 0.561 |
TMEM208 | TMEM54 | ENSP00000305892 | ENSP00000362562 | Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy | Transmembrane protein 54 | 0.480 |
TMEM208 | ZNF205 | ENSP00000305892 | ENSP00000480401 | Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy | Zinc finger protein 205; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.480 |
TMEM54 | BTBD8 | ENSP00000362562 | ENSP00000343686 | Transmembrane protein 54 | BTB/POZ domain-containing protein 8; BTB domain containing 8 | 0.473 |
TMEM54 | RARS2 | ENSP00000362562 | ENSP00000358549 | Transmembrane protein 54 | Probable arginine--tRNA ligase, mitochondrial; arginyl-tRNA synthetase 2, mitochondrial; Aminoacyl tRNA synthetases, Class I | 0.531 |