• Version:
  • 11.0 [archived version]
STRINGSTRING
CCDC101 CCDC101 DERA DERA HM13 HM13 ERI3 ERI3 SNAP29 SNAP29 NIPSNAP3A NIPSNAP3A C1orf122 C1orf122 SLC41A1 SLC41A1 MANEA MANEA TXLNA TXLNA TXLNB TXLNB
"C1orf122" - Uncharacterized protein C1orf122 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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C1orf122Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 (110 aa)    
Predicted Functional Partners:
TXLNB
Beta-taxilin; Promotes motor nerve regeneration (By similarity). May be involved in intracellular vesicle traffic; Belongs to the taxilin family (684 aa)
       
      0.741
TXLNA
Alpha-taxilin; May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells; Belongs to the taxilin family (546 aa)
       
      0.656
NIPSNAP3A
Nipsnap homolog 3A; Belongs to the NipSnap family (247 aa)
           
  0.645
ERI3
ERI1 exoribonuclease family member 3; Exonucleases (337 aa)
     
   
  0.556
CCDC101
SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated ’Lys-4’ of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival (293 aa)
       
      0.549
HM13
Histocompatibility minor 13 (426 aa)
     
   
  0.540
SNAP29
Synaptosomal-associated protein 29; SNAREs, soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions; Belongs to the SNAP-25 family (258 aa)
       
      0.536
MANEA
Glycoprotein endo-alpha-1,2-mannosidase; Mannosidases endo-alpha (462 aa)
           
  0.531
SLC41A1
Solute carrier family 41 member 1; Acts as a magnesium transporter that is responsive to magnesium balance; Solute carriers (513 aa)
           
  0.531
DERA
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation (318 aa)
           
  0.516
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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