node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf122 | CCDC101 | ENSP00000362133 | ENSP00000316114 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated ’Lys-4’ of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival | 0.549 |
C1orf122 | DERA | ENSP00000362133 | ENSP00000416583 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation | 0.516 |
C1orf122 | ERI3 | ENSP00000362133 | ENSP00000361331 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | ERI1 exoribonuclease family member 3; Exonucleases | 0.556 |
C1orf122 | HM13 | ENSP00000362133 | ENSP00000381237 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | Histocompatibility minor 13 | 0.540 |
C1orf122 | MANEA | ENSP00000362133 | ENSP00000351669 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | Glycoprotein endo-alpha-1,2-mannosidase; Mannosidases endo-alpha | 0.531 |
C1orf122 | NIPSNAP3A | ENSP00000362133 | ENSP00000363899 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | Nipsnap homolog 3A; Belongs to the NipSnap family | 0.645 |
C1orf122 | SLC41A1 | ENSP00000362133 | ENSP00000356105 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | Solute carrier family 41 member 1; Acts as a magnesium transporter that is responsive to magnesium balance; Solute carriers | 0.531 |
C1orf122 | SNAP29 | ENSP00000362133 | ENSP00000215730 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | Synaptosomal-associated protein 29; SNAREs, soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions; Belongs to the SNAP-25 family | 0.536 |
C1orf122 | TXLNA | ENSP00000362133 | ENSP00000362711 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | Alpha-taxilin; May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells; Belongs to the taxilin family | 0.656 |
C1orf122 | TXLNB | ENSP00000362133 | ENSP00000351206 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | Beta-taxilin; Promotes motor nerve regeneration (By similarity). May be involved in intracellular vesicle traffic; Belongs to the taxilin family | 0.741 |
CCDC101 | C1orf122 | ENSP00000316114 | ENSP00000362133 | SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated ’Lys-4’ of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | 0.549 |
DERA | C1orf122 | ENSP00000416583 | ENSP00000362133 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | 0.516 |
DERA | NIPSNAP3A | ENSP00000416583 | ENSP00000363899 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation | Nipsnap homolog 3A; Belongs to the NipSnap family | 0.484 |
ERI3 | C1orf122 | ENSP00000361331 | ENSP00000362133 | ERI1 exoribonuclease family member 3; Exonucleases | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | 0.556 |
ERI3 | NIPSNAP3A | ENSP00000361331 | ENSP00000363899 | ERI1 exoribonuclease family member 3; Exonucleases | Nipsnap homolog 3A; Belongs to the NipSnap family | 0.518 |
HM13 | C1orf122 | ENSP00000381237 | ENSP00000362133 | Histocompatibility minor 13 | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | 0.540 |
HM13 | NIPSNAP3A | ENSP00000381237 | ENSP00000363899 | Histocompatibility minor 13 | Nipsnap homolog 3A; Belongs to the NipSnap family | 0.477 |
HM13 | SLC41A1 | ENSP00000381237 | ENSP00000356105 | Histocompatibility minor 13 | Solute carrier family 41 member 1; Acts as a magnesium transporter that is responsive to magnesium balance; Solute carriers | 0.452 |
MANEA | C1orf122 | ENSP00000351669 | ENSP00000362133 | Glycoprotein endo-alpha-1,2-mannosidase; Mannosidases endo-alpha | Uncharacterized protein C1orf122; Chromosome 1 open reading frame 122 | 0.531 |
MANEA | NIPSNAP3A | ENSP00000351669 | ENSP00000363899 | Glycoprotein endo-alpha-1,2-mannosidase; Mannosidases endo-alpha | Nipsnap homolog 3A; Belongs to the NipSnap family | 0.502 |