node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGAP17 | OSER1 | ENSP00000289968 | ENSP00000362061 | Rho GTPase-activating protein 17; Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent [...] | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | 0.636 |
C1orf174 | HAGHL | ENSP00000355306 | ENSP00000374353 | UPF0688 protein C1orf174; Chromosome 1 open reading frame 174; Belongs to the UPF0688 family | Hydroxyacylglutathione hydrolase-like protein; Hydrolase acting on ester bonds | 0.587 |
C1orf174 | OSER1 | ENSP00000355306 | ENSP00000362061 | UPF0688 protein C1orf174; Chromosome 1 open reading frame 174; Belongs to the UPF0688 family | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | 0.530 |
C2orf73 | LRRC66 | ENSP00000381631 | ENSP00000341944 | Uncharacterized protein C2orf73; Chromosome 2 open reading frame 73 | Leucine-rich repeat-containing protein 66; Leucine rich repeat containing 66 | 0.576 |
C2orf73 | OSER1 | ENSP00000381631 | ENSP00000362061 | Uncharacterized protein C2orf73; Chromosome 2 open reading frame 73 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | 0.491 |
HAGHL | C1orf174 | ENSP00000374353 | ENSP00000355306 | Hydroxyacylglutathione hydrolase-like protein; Hydrolase acting on ester bonds | UPF0688 protein C1orf174; Chromosome 1 open reading frame 174; Belongs to the UPF0688 family | 0.587 |
HAGHL | OSER1 | ENSP00000374353 | ENSP00000362061 | Hydroxyacylglutathione hydrolase-like protein; Hydrolase acting on ester bonds | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | 0.480 |
LRRC66 | C2orf73 | ENSP00000341944 | ENSP00000381631 | Leucine-rich repeat-containing protein 66; Leucine rich repeat containing 66 | Uncharacterized protein C2orf73; Chromosome 2 open reading frame 73 | 0.576 |
LRRC66 | OSER1 | ENSP00000341944 | ENSP00000362061 | Leucine-rich repeat-containing protein 66; Leucine rich repeat containing 66 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | 0.511 |
OSER1 | ARHGAP17 | ENSP00000362061 | ENSP00000289968 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | Rho GTPase-activating protein 17; Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent [...] | 0.636 |
OSER1 | C1orf174 | ENSP00000362061 | ENSP00000355306 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | UPF0688 protein C1orf174; Chromosome 1 open reading frame 174; Belongs to the UPF0688 family | 0.530 |
OSER1 | C2orf73 | ENSP00000362061 | ENSP00000381631 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | Uncharacterized protein C2orf73; Chromosome 2 open reading frame 73 | 0.491 |
OSER1 | HAGHL | ENSP00000362061 | ENSP00000374353 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | Hydroxyacylglutathione hydrolase-like protein; Hydrolase acting on ester bonds | 0.480 |
OSER1 | LRRC66 | ENSP00000362061 | ENSP00000341944 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | Leucine-rich repeat-containing protein 66; Leucine rich repeat containing 66 | 0.511 |
OSER1 | ROMO1 | ENSP00000362061 | ENSP00000363191 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | Reactive oxygen species modulator 1; Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation; Belongs to the MGR2 family | 0.520 |
OSER1 | RPUSD2 | ENSP00000362061 | ENSP00000323288 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | RNA pseudouridylate synthase domain containing 2 | 0.471 |
OSER1 | ZFAND1 | ENSP00000362061 | ENSP00000220669 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | Zinc finger AN1-type containing 1 | 0.511 |
OSER1 | ZFAND2A | ENSP00000362061 | ENSP00000314619 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | Zinc finger AN1-type containing 2A | 0.755 |
OSER1 | ZFAND2B | ENSP00000362061 | ENSP00000289528 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | Zinc finger AN1-type containing 2B | 0.817 |
ROMO1 | OSER1 | ENSP00000363191 | ENSP00000362061 | Reactive oxygen species modulator 1; Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation; Belongs to the MGR2 family | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 | 0.520 |