KCNK15 protein (human) - STRING database

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KCNK15

Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K (330 aa)

Predicted Functional Partners:

KCNS1

0.803

GYG1

0.758

NUDT6

0.756

UNC93A

0.573

KIF6

0.523

SLC24A3

0.509

CLNK

0.469

C1orf146

0.448

C16orf70

0.444

IKBKG

0.441

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C16orf70	KCNK15	ENSP00000219139	ENSP00000361952	UPF0183 protein C16orf70; Chromosome 16 open reading frame 70; Belongs to the UPF0183 family	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	0.444
C1orf146	KCNK15	ENSP00000359401	ENSP00000361952	Uncharacterized protein C1orf146; Chromosome 1 open reading frame 146	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	0.448
CLNK	KCNK15	ENSP00000226951	ENSP00000361952	Cytokine-dependent hematopoietic cell linker; Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT (By similarity); SH2 domain containing	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	0.469
GYG1	KCNK15	ENSP00000340736	ENSP00000361952	Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	0.758
GYG1	KCNS1	ENSP00000340736	ENSP00000307694	Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8	Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage- gated potassium channel activation and deactivation rates of KCNB1 and KCNB2	0.424
GYG1	NUDT6	ENSP00000340736	ENSP00000306070	Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8	Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family	0.884
IKBKG	KCNK15	ENSP00000483825	ENSP00000361952	NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either ’Lys-63’- linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activat [...]	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	0.441
KCNK15	C16orf70	ENSP00000361952	ENSP00000219139	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	UPF0183 protein C16orf70; Chromosome 16 open reading frame 70; Belongs to the UPF0183 family	0.444
KCNK15	C1orf146	ENSP00000361952	ENSP00000359401	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	Uncharacterized protein C1orf146; Chromosome 1 open reading frame 146	0.448
KCNK15	CLNK	ENSP00000361952	ENSP00000226951	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	Cytokine-dependent hematopoietic cell linker; Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT (By similarity); SH2 domain containing	0.469
KCNK15	GYG1	ENSP00000361952	ENSP00000340736	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8	0.758
KCNK15	IKBKG	ENSP00000361952	ENSP00000483825	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either ’Lys-63’- linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activat [...]	0.441
KCNK15	KCNS1	ENSP00000361952	ENSP00000307694	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage- gated potassium channel activation and deactivation rates of KCNB1 and KCNB2	0.803
KCNK15	KIF6	ENSP00000361952	ENSP00000287152	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	Kinesin-like protein KIF6; Kinesin family member 6; Kinesins	0.523
KCNK15	NUDT6	ENSP00000361952	ENSP00000306070	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family	0.756
KCNK15	SLC24A3	ENSP00000361952	ENSP00000333519	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	Sodium/potassium/calcium exchanger 3; Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+); Solute carriers	0.509
KCNK15	UNC93A	ENSP00000361952	ENSP00000230256	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	Unc-93 homolog A; Belongs to the unc-93 family	0.573
KCNS1	GYG1	ENSP00000307694	ENSP00000340736	Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage- gated potassium channel activation and deactivation rates of KCNB1 and KCNB2	Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8	0.424
KCNS1	KCNK15	ENSP00000307694	ENSP00000361952	Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage- gated potassium channel activation and deactivation rates of KCNB1 and KCNB2	Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K	0.803
KCNS1	NUDT6	ENSP00000307694	ENSP00000306070	Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage- gated potassium channel activation and deactivation rates of KCNB1 and KCNB2	Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family	0.442

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