| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQP4 | HPCAL4 | ENSP00000372654 | ENSP00000361935 | Aquaporin-4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system; Belongs to the MIP/aquaporin (TC 1.A.8) family | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | 0.562 |
| CALY | HPCAL4 | ENSP00000252939 | ENSP00000361935 | Neuron-specific vesicular protein calcyon; Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | 0.678 |
| CAMKV | HPCAL4 | ENSP00000419195 | ENSP00000361935 | CaM kinase-like vesicle-associated protein; Does not appear to have detectable kinase activity; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | 0.571 |
| DGKG | HPCAL4 | ENSP00000265022 | ENSP00000361935 | Diacylglycerol kinase gamma; Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid; Belongs to the eukaryotic diacylglycerol kinase family | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | 0.585 |
| DGKG | RNPEP | ENSP00000265022 | ENSP00000295640 | Diacylglycerol kinase gamma; Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid; Belongs to the eukaryotic diacylglycerol kinase family | Aminopeptidase B; Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(- 1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4) (By similarity) | 0.463 |
| FAM131C | HPCAL4 | ENSP00000364814 | ENSP00000361935 | Protein FAM131C; Family with sequence similarity 131 member C | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | 0.751 |
| HPCAL4 | AQP4 | ENSP00000361935 | ENSP00000372654 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | Aquaporin-4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system; Belongs to the MIP/aquaporin (TC 1.A.8) family | 0.562 |
| HPCAL4 | CALY | ENSP00000361935 | ENSP00000252939 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | Neuron-specific vesicular protein calcyon; Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis | 0.678 |
| HPCAL4 | CAMKV | ENSP00000361935 | ENSP00000419195 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | CaM kinase-like vesicle-associated protein; Does not appear to have detectable kinase activity; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family | 0.571 |
| HPCAL4 | DGKG | ENSP00000361935 | ENSP00000265022 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | Diacylglycerol kinase gamma; Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid; Belongs to the eukaryotic diacylglycerol kinase family | 0.585 |
| HPCAL4 | FAM131C | ENSP00000361935 | ENSP00000364814 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | Protein FAM131C; Family with sequence similarity 131 member C | 0.751 |
| HPCAL4 | NXT2 | ENSP00000361935 | ENSP00000218004 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | NTF2-related export protein 2; Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export | 0.563 |
| HPCAL4 | POLE4 | ENSP00000361935 | ENSP00000420176 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | DNA polymerase epsilon subunit 4; May play a role in allowing polymerase epsilon to carry out its replication and/or repair function; DNA polymerases | 0.580 |
| HPCAL4 | RNPEP | ENSP00000361935 | ENSP00000295640 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | Aminopeptidase B; Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(- 1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4) (By similarity) | 0.653 |
| HPCAL4 | RSBN1 | ENSP00000361935 | ENSP00000261441 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated ’Lys-20’ of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family | 0.611 |
| HPCAL4 | TMOD2 | ENSP00000361935 | ENSP00000249700 | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | Tropomodulin-2; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity); Tropomodulins | 0.565 |
| NXT2 | HPCAL4 | ENSP00000218004 | ENSP00000361935 | NTF2-related export protein 2; Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | 0.563 |
| NXT2 | POLE4 | ENSP00000218004 | ENSP00000420176 | NTF2-related export protein 2; Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export | DNA polymerase epsilon subunit 4; May play a role in allowing polymerase epsilon to carry out its replication and/or repair function; DNA polymerases | 0.421 |
| NXT2 | RSBN1 | ENSP00000218004 | ENSP00000261441 | NTF2-related export protein 2; Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export | Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated ’Lys-20’ of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family | 0.502 |
| POLE4 | HPCAL4 | ENSP00000420176 | ENSP00000361935 | DNA polymerase epsilon subunit 4; May play a role in allowing polymerase epsilon to carry out its replication and/or repair function; DNA polymerases | Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing | 0.580 |
