node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMCX4 | BEX5 | ENSP00000404304 | ENSP00000446054 | Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | 0.463 |
ARMCX4 | TCEAL2 | ENSP00000404304 | ENSP00000361866 | Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.587 |
BEX1 | GPRASP1 | ENSP00000361813 | ENSP00000445683 | Protein BEX1; Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity); Brain expressed X-linked family | G-protein coupled receptor-associated sorting protein 1; Modulates lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2; Armadillo repeat containing | 0.658 |
BEX1 | TCEAL2 | ENSP00000361813 | ENSP00000361866 | Protein BEX1; Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity); Brain expressed X-linked family | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.532 |
BEX5 | ARMCX4 | ENSP00000446054 | ENSP00000404304 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family | 0.463 |
BEX5 | MORF4L2 | ENSP00000446054 | ENSP00000394417 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | 0.488 |
BEX5 | TCEAL2 | ENSP00000446054 | ENSP00000361866 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.673 |
GPRASP1 | BEX1 | ENSP00000445683 | ENSP00000361813 | G-protein coupled receptor-associated sorting protein 1; Modulates lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2; Armadillo repeat containing | Protein BEX1; Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity); Brain expressed X-linked family | 0.658 |
GPRASP1 | TCEAL2 | ENSP00000445683 | ENSP00000361866 | G-protein coupled receptor-associated sorting protein 1; Modulates lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2; Armadillo repeat containing | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.566 |
MORF4L2 | BEX5 | ENSP00000394417 | ENSP00000446054 | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | 0.488 |
MORF4L2 | TCEAL1 | ENSP00000394417 | ENSP00000361708 | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | Transcription elongation factor A like family | 0.452 |
MORF4L2 | TCEAL2 | ENSP00000394417 | ENSP00000361866 | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.551 |
SERTM1 | TCEAL2 | ENSP00000325776 | ENSP00000361866 | Serine rich and transmembrane domain containing 1 | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.537 |
TCEAL1 | MORF4L2 | ENSP00000361708 | ENSP00000394417 | Transcription elongation factor A like family | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | 0.452 |
TCEAL1 | TCEAL2 | ENSP00000361708 | ENSP00000361866 | Transcription elongation factor A like family | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.651 |
TCEAL1 | TCEAL4 | ENSP00000361708 | ENSP00000361712 | Transcription elongation factor A like family | Transcription elongation factor A protein-like 4; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.913 |
TCEAL1 | USP11 | ENSP00000361708 | ENSP00000218348 | Transcription elongation factor A like family | Ubiquitin carboxyl-terminal hydrolase 11; Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially ’Lys-6’ and ’Lys-63’-linked ubiquitin chains. Has lower activity with ’Lys-11’ and ’Lys-33’-linked ubiquitin chains, and extremely low activity with ’Lys-27’, ’Lys-29’ and ’Lys-48’- linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA break [...] | 0.839 |
TCEAL2 | ARMCX4 | ENSP00000361866 | ENSP00000404304 | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family | 0.587 |
TCEAL2 | BEX1 | ENSP00000361866 | ENSP00000361813 | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | Protein BEX1; Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity); Brain expressed X-linked family | 0.532 |
TCEAL2 | BEX5 | ENSP00000361866 | ENSP00000446054 | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | 0.673 |