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  • 11.0 [archived version]
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ARMCX4 ARMCX4 GPRASP1 GPRASP1 BEX5 BEX5 BEX1 BEX1 MORF4L2 MORF4L2 TCEAL2 TCEAL2 SERTM1 SERTM1 TCEAL1 TCEAL1 TCEAL4 TCEAL4 TCEAL8 TCEAL8 USP11 USP11
"TCEAL2" - Transcription elongation factor A protein-like 2 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TCEAL2Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family (227 aa)    
Predicted Functional Partners:
BEX5
Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family (111 aa)
     
   
  0.673
TCEAL1
Transcription elongation factor A like family (159 aa)
     
 
  0.651
TCEAL4
Transcription elongation factor A protein-like 4; May be involved in transcriptional regulation; Transcription elongation factor A like family (358 aa)
     
   
0.599
ARMCX4
Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family (2290 aa)
     
   
  0.587
TCEAL8
Transcription elongation factor A protein-like 8; May be involved in transcriptional regulation; Transcription elongation factor A like family (117 aa)
     
   
  0.569
GPRASP1
G-protein coupled receptor-associated sorting protein 1; Modulates lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2; Armadillo repeat containing (1395 aa)
     
   
  0.566
MORF4L2
Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] (288 aa)
           
  0.551
SERTM1
Serine rich and transmembrane domain containing 1 (107 aa)
     
   
  0.537
BEX1
Protein BEX1; Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity); Brain expressed X-linked family (125 aa)
     
   
  0.532
USP11
Ubiquitin carboxyl-terminal hydrolase 11; Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially ’Lys-6’ and ’Lys-63’-linked ubiquitin chains. Has lower activity with ’Lys-11’ and ’Lys-33’-linked ubiquitin chains, and extremely low activity with ’Lys-27’, ’Lys-29’ and ’Lys-48’- linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA break [...] (963 aa)
     
      0.523
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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