WFDC2 protein (human) - STRING database

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Score

WFDC2

WAP four-disulfide core domain protein 2; Broad range protease inhibitor; WAP four-disulfide core domain containing (124 aa)

Predicted Functional Partners:

SPINT3

0.629

SLPI

0.614

SPINT4

0.605

WFDC9

0.603

WFDC10A

0.583

MSLN

0.568

WFDC13

0.563

CSRP2

0.559

WFDC8

0.557

LY6G5C

0.544

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSRP2	WFDC2	ENSP00000310901	ENSP00000361761	Cysteine and glycine-rich protein 2; Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system; LIM domain containing	WAP four-disulfide core domain protein 2; Broad range protease inhibitor; WAP four-disulfide core domain containing	0.559
LY6G5C	WFDC2	ENSP00000372724	ENSP00000361761	Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation; LY6/PLAUR domain containing	WAP four-disulfide core domain protein 2; Broad range protease inhibitor; WAP four-disulfide core domain containing	0.544
MSLN	WFDC2	ENSP00000372313	ENSP00000361761	Mesothelin; Membrane-anchored forms may play a role in cellular adhesion	WAP four-disulfide core domain protein 2; Broad range protease inhibitor; WAP four-disulfide core domain containing	0.568
SLPI	WFDC2	ENSP00000342082	ENSP00000361761	Antileukoproteinase; Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS) (By similarity). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for nor [...]	WAP four-disulfide core domain protein 2; Broad range protease inhibitor; WAP four-disulfide core domain containing	0.614
SLPI	WFDC8	ENSP00000342082	ENSP00000361735	Antileukoproteinase; Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS) (By similarity). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for nor [...]	WAP four-disulfide core domain containing	0.442
SPINT3	SPINT4	ENSP00000217428	ENSP00000279058	Serine peptidase inhibitor, Kunitz type 3	Serine peptidase inhibitor, Kunitz type 4	0.671
SPINT3	WFDC10A	ENSP00000217428	ENSP00000361726	Serine peptidase inhibitor, Kunitz type 3	WAP four-disulfide core domain containing	0.690
SPINT3	WFDC13	ENSP00000217428	ENSP00000302938	Serine peptidase inhibitor, Kunitz type 3	WAP four-disulfide core domain protein 13; Putative acid-stable proteinase inhibitor; WAP four-disulfide core domain containing	0.595
SPINT3	WFDC2	ENSP00000217428	ENSP00000361761	Serine peptidase inhibitor, Kunitz type 3	WAP four-disulfide core domain protein 2; Broad range protease inhibitor; WAP four-disulfide core domain containing	0.629
SPINT3	WFDC8	ENSP00000217428	ENSP00000361735	Serine peptidase inhibitor, Kunitz type 3	WAP four-disulfide core domain containing	0.676
SPINT3	WFDC9	ENSP00000217428	ENSP00000320532	Serine peptidase inhibitor, Kunitz type 3	Protein WFDC9; WAP four-disulfide core domain containing	0.720
SPINT4	SPINT3	ENSP00000279058	ENSP00000217428	Serine peptidase inhibitor, Kunitz type 4	Serine peptidase inhibitor, Kunitz type 3	0.671
SPINT4	WFDC10A	ENSP00000279058	ENSP00000361726	Serine peptidase inhibitor, Kunitz type 4	WAP four-disulfide core domain containing	0.642
SPINT4	WFDC13	ENSP00000279058	ENSP00000302938	Serine peptidase inhibitor, Kunitz type 4	WAP four-disulfide core domain protein 13; Putative acid-stable proteinase inhibitor; WAP four-disulfide core domain containing	0.754
SPINT4	WFDC2	ENSP00000279058	ENSP00000361761	Serine peptidase inhibitor, Kunitz type 4	WAP four-disulfide core domain protein 2; Broad range protease inhibitor; WAP four-disulfide core domain containing	0.605
SPINT4	WFDC8	ENSP00000279058	ENSP00000361735	Serine peptidase inhibitor, Kunitz type 4	WAP four-disulfide core domain containing	0.825
SPINT4	WFDC9	ENSP00000279058	ENSP00000320532	Serine peptidase inhibitor, Kunitz type 4	Protein WFDC9; WAP four-disulfide core domain containing	0.686
WFDC10A	SPINT3	ENSP00000361726	ENSP00000217428	WAP four-disulfide core domain containing	Serine peptidase inhibitor, Kunitz type 3	0.690
WFDC10A	SPINT4	ENSP00000361726	ENSP00000279058	WAP four-disulfide core domain containing	Serine peptidase inhibitor, Kunitz type 4	0.642
WFDC10A	WFDC13	ENSP00000361726	ENSP00000302938	WAP four-disulfide core domain containing	WAP four-disulfide core domain protein 13; Putative acid-stable proteinase inhibitor; WAP four-disulfide core domain containing	0.802

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