• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF540 ZNF540 TMEM179 TMEM179 SERINC2 SERINC2 NRIP2 NRIP2 ZNF454 ZNF454 GPHN GPHN ZDHHC12 ZDHHC12 ZNF419 ZNF419 TMEM134 TMEM134 KIAA1551 KIAA1551 REEP6 REEP6
"ZDHHC12" - Probable palmitoyltransferase ZDHHC12 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
ZDHHC12Probable palmitoyltransferase ZDHHC12; Zinc finger DHHC-type containing 12; Belongs to the DHHC palmitoyltransferase family (267 aa)    
Predicted Functional Partners:
ZNF454
Zinc finger protein 454; May be involved in transcriptional regulation; Zinc fingers C2H2-type (522 aa)
       
 
  0.498
GPHN
Gephyrin; Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released; In the C-terminal section; belongs to the MoeA family (769 aa)
           
  0.481
ZNF540
Zinc finger protein 540; May act as a transcriptional repressor; Zinc fingers C2H2-type (660 aa)
       
 
  0.478
TMEM179
Transmembrane protein 179; Belongs to the TMEM179 family (233 aa)
           
  0.478
TMEM134
Transmembrane protein 134 (195 aa)
           
  0.473
KIAA1551
Uncharacterized protein KIAA1551; Minor histocompatibility antigens (1747 aa)
           
  0.471
NRIP2
Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 (281 aa)
     
   
  0.467
ZNF419
Zinc finger protein 419; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (511 aa)
       
 
  0.456
SERINC2
Serine incorporator 2; Belongs to the TDE1 family (464 aa)
     
   
  0.445
REEP6
Receptor accessory protein 6 (184 aa)
     
   
  0.409
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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