• Version:
  • 11.0 [archived version]
STRINGSTRING
ADPRHL1 ADPRHL1 TRIM74 TRIM74 TCEAL8 TCEAL8 TCEAL4 TCEAL4 NUDCD2 NUDCD2 TCEAL2 TCEAL2 BZW1 BZW1 USP11 USP11 GPATCH2L GPATCH2L TCEAL1 TCEAL1 TCEAL7 TCEAL7
"TCEAL4" - Transcription elongation factor A protein-like 4 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
TCEAL4Transcription elongation factor A protein-like 4; May be involved in transcriptional regulation; Transcription elongation factor A like family (358 aa)    
Predicted Functional Partners:
TCEAL1
Transcription elongation factor A like family (159 aa)
     
 
  0.913
TCEAL8
Transcription elongation factor A protein-like 8; May be involved in transcriptional regulation; Transcription elongation factor A like family (117 aa)
     
   
  0.748
TCEAL2
Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family (227 aa)
     
   
0.599
NUDCD2
NudC domain-containing protein 2; May regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone; NudC family (157 aa)
           
  0.586
TCEAL7
Transcription elongation factor A protein-like 7; Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines; Transcription elongation factor A like family (100 aa)
     
   
  0.569
USP11
Ubiquitin carboxyl-terminal hydrolase 11; Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially ’Lys-6’ and ’Lys-63’-linked ubiquitin chains. Has lower activity with ’Lys-11’ and ’Lys-33’-linked ubiquitin chains, and extremely low activity with ’Lys-27’, ’Lys-29’ and ’Lys-48’- linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA break [...] (963 aa)
     
      0.521
TRIM74
Tripartite motif containing 74; Belongs to the TRIM/RBCC family (250 aa)
           
  0.519
ADPRHL1
[Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1 (354 aa)
       
      0.510
GPATCH2L
G patch domain-containing protein 2-like; G-patch domain containing 2 like (482 aa)
           
  0.506
BZW1
Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly (451 aa)
           
  0.492
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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