• Version:
  • 11.0 [archived version]
STRINGSTRING
RDH14 RDH14 KLHL30 KLHL30 DQX1 DQX1 KLHDC7A KLHDC7A C1orf50 C1orf50 EPM2AIP1 EPM2AIP1 ZDHHC23 ZDHHC23 CCDC89 CCDC89 AHCY AHCY KIAA0232 KIAA0232 SIPA1L3 SIPA1L3
"C1orf50" - Uncharacterized protein C1orf50 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1orf50Uncharacterized protein C1orf50; Chromosome 1 open reading frame 50 (199 aa)    
Predicted Functional Partners:
AHCY
Adenosylhomocysteinase; Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine (432 aa)
       
      0.923
EPM2AIP1
EPM2A interacting protein 1 (607 aa)
       
      0.686
DQX1
ATP-dependent RNA helicase DQX1; DEAQ-box RNA dependent ATPase 1 (717 aa)
           
  0.559
CCDC89
Coiled-coil domain containing 89; Belongs to the CCDC89 family (374 aa)
           
  0.550
KLHL30
Kelch-like protein 30; Kelch like family member 30; BTB domain containing (578 aa)
           
  0.530
KIAA0232
Uncharacterized protein KIAA0232; KIAA0232 (1395 aa)
           
  0.522
KLHDC7A
Kelch domain containing 7A (777 aa)
           
  0.519
RDH14
Retinol dehydrogenase 14; Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected; Short chain dehydrogenase/reductase superfamily (336 aa)
     
   
  0.464
SIPA1L3
Signal-induced proliferation-associated 1-like protein 3; Plays a critical role in epithelial cell morphogenesis, polarity, adhesion and cytoskeletal organization in the lens; PDZ domain containing (1781 aa)
           
  0.461
ZDHHC23
Palmitoyltransferase ZDHHC23; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. May be involved in NOS1 regulation and targeting to the synaptic membrane; Zinc fingers DHHC-type (409 aa)
           
  0.455
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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