node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERICH1 | FBXO25 | ENSP00000262109 | ENSP00000372274 | Glutamate-rich protein 1; Glutamate rich 1 | F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity); F-boxes other | 0.652 |
ERICH1 | PCIF1 | ENSP00000262109 | ENSP00000361486 | Glutamate-rich protein 1; Glutamate rich 1 | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | 0.684 |
ERICH1 | PXDC1 | ENSP00000262109 | ENSP00000369636 | Glutamate-rich protein 1; Glutamate rich 1 | PX domain containing 1 | 0.698 |
ERICH1 | RSBN1L | ENSP00000262109 | ENSP00000334040 | Glutamate-rich protein 1; Glutamate rich 1 | Round spermatid basic protein 1 like | 0.632 |
ERICH1 | SLC22A23 | ENSP00000262109 | ENSP00000385028 | Glutamate-rich protein 1; Glutamate rich 1 | Solute carrier family 22 member 23 | 0.657 |
ERICH1 | STON2 | ENSP00000262109 | ENSP00000450857 | Glutamate-rich protein 1; Glutamate rich 1 | Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family | 0.578 |
FBXO25 | ERICH1 | ENSP00000372274 | ENSP00000262109 | F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity); F-boxes other | Glutamate-rich protein 1; Glutamate rich 1 | 0.652 |
FBXO25 | PCIF1 | ENSP00000372274 | ENSP00000361486 | F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity); F-boxes other | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | 0.557 |
FBXO25 | PXDC1 | ENSP00000372274 | ENSP00000369636 | F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity); F-boxes other | PX domain containing 1 | 0.569 |
FBXO25 | RSBN1L | ENSP00000372274 | ENSP00000334040 | F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity); F-boxes other | Round spermatid basic protein 1 like | 0.524 |
FBXO25 | SLC22A23 | ENSP00000372274 | ENSP00000385028 | F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity); F-boxes other | Solute carrier family 22 member 23 | 0.516 |
FBXO25 | STON2 | ENSP00000372274 | ENSP00000450857 | F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity); F-boxes other | Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family | 0.459 |
KATNAL1 | PCIF1 | ENSP00000369989 | ENSP00000361486 | Katanin p60 ATPase-containing subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro; Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | 0.592 |
PCIF1 | ERICH1 | ENSP00000361486 | ENSP00000262109 | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | Glutamate-rich protein 1; Glutamate rich 1 | 0.684 |
PCIF1 | FBXO25 | ENSP00000361486 | ENSP00000372274 | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity); F-boxes other | 0.557 |
PCIF1 | KATNAL1 | ENSP00000361486 | ENSP00000369989 | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | Katanin p60 ATPase-containing subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro; Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily | 0.592 |
PCIF1 | PDX1 | ENSP00000361486 | ENSP00000370421 | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | Pancreas/duodenum homeobox protein 1; Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1-PBX1b-MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5’-[CT]TAAT[TG]-3’. During development [...] | 0.646 |
PCIF1 | PSAPL1 | ENSP00000361486 | ENSP00000317445 | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids | 0.663 |
PCIF1 | PXDC1 | ENSP00000361486 | ENSP00000369636 | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | PX domain containing 1 | 0.669 |
PCIF1 | RSBN1L | ENSP00000361486 | ENSP00000334040 | Phosphorylated CTD-interacting factor 1; May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit; Protein phosphatase 1 regulatory subunits | Round spermatid basic protein 1 like | 0.626 |