SLC2A6 protein (human) - STRING database

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SLC2A6

Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily (507 aa)

Predicted Functional Partners:

SLC12A9

0.700

EIF2AK4

0.676

SLC10A3

0.647

BZRAP1

0.615

SLC15A4

0.542

SLC7A6

0.521

EP400NL

0.495

ENSG00000251357

0.491

RABEPK

0.489

SLC2A11

0.471

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BZRAP1	RABEPK	ENSP00000345824	ENSP00000362639	Benzodiazepine receptor (peripheral) associated protein 1; Belongs to the RIMBP family	Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport	0.479
BZRAP1	SLC12A9	ENSP00000345824	ENSP00000275730	Benzodiazepine receptor (peripheral) associated protein 1; Belongs to the RIMBP family	Solute carrier family 12 member 9; May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function; Solute carriers	0.665
BZRAP1	SLC2A6	ENSP00000345824	ENSP00000360966	Benzodiazepine receptor (peripheral) associated protein 1; Belongs to the RIMBP family	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	0.615
BZRAP1	SLC7A6	ENSP00000345824	ENSP00000455064	Benzodiazepine receptor (peripheral) associated protein 1; Belongs to the RIMBP family	Y+L amino acid transporter 2; Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in mono [...]	0.403
EIF2AK4	SLC2A6	ENSP00000263791	ENSP00000360966	eIF-2-alpha kinase GCN2; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2-alpha/EIF2S1) on ’Ser-52’ in response to low amino acid availability. Plays a role as an activator of the integrated stress response (ISR) required for adapatation to amino acid starvation. Converts phosphorylated eIF- 2-alpha/EIF2S1 either to a competitive inhibitor of the translation initiation factor eIF-2B, leading to a global protein synthesis repression, and thus to a reduced overall utilization of amino acids, or to a transla [...]	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	0.676
ENSG00000251357	SLC2A6	ENSP00000400325	ENSP00000360966	Uncharacterized protein	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	0.491
EP400NL	SLC2A6	ENSP00000374211	ENSP00000360966	EP400 N-terminal-like protein; EP400 N-terminal like	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	0.495
RABEPK	BZRAP1	ENSP00000362639	ENSP00000345824	Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport	Benzodiazepine receptor (peripheral) associated protein 1; Belongs to the RIMBP family	0.479
RABEPK	SLC12A9	ENSP00000362639	ENSP00000275730	Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport	Solute carrier family 12 member 9; May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function; Solute carriers	0.423
RABEPK	SLC2A6	ENSP00000362639	ENSP00000360966	Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	0.489
SLC10A3	SLC15A4	ENSP00000263512	ENSP00000266771	P3 protein; The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions; Solute carriers	Solute carrier family 15 member 4; Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides; Solute carriers	0.632
SLC10A3	SLC2A6	ENSP00000263512	ENSP00000360966	P3 protein; The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions; Solute carriers	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	0.647
SLC12A9	BZRAP1	ENSP00000275730	ENSP00000345824	Solute carrier family 12 member 9; May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function; Solute carriers	Benzodiazepine receptor (peripheral) associated protein 1; Belongs to the RIMBP family	0.665
SLC12A9	RABEPK	ENSP00000275730	ENSP00000362639	Solute carrier family 12 member 9; May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function; Solute carriers	Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport	0.423
SLC12A9	SLC2A6	ENSP00000275730	ENSP00000360966	Solute carrier family 12 member 9; May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function; Solute carriers	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	0.700
SLC12A9	SLC7A6	ENSP00000275730	ENSP00000455064	Solute carrier family 12 member 9; May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function; Solute carriers	Y+L amino acid transporter 2; Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in mono [...]	0.466
SLC15A4	SLC10A3	ENSP00000266771	ENSP00000263512	Solute carrier family 15 member 4; Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides; Solute carriers	P3 protein; The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions; Solute carriers	0.632
SLC15A4	SLC2A6	ENSP00000266771	ENSP00000360966	Solute carrier family 15 member 4; Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides; Solute carriers	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	0.542
SLC2A11	SLC2A6	ENSP00000483038	ENSP00000360966	Solute carrier family 2, facilitated glucose transporter member 11; Facilitative glucose transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	0.471
SLC2A6	BZRAP1	ENSP00000360966	ENSP00000345824	Solute carrier family 2, facilitated glucose transporter member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily	Benzodiazepine receptor (peripheral) associated protein 1; Belongs to the RIMBP family	0.615

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