node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRI3BP | CCDC57 | ENSP00000340761 | ENSP00000374292 | BRI3-binding protein; Involved in tumorigenesis and may function by stabilizing p53/TP53 | Coiled-coil domain containing 57 | 0.706 |
BRI3BP | GLT6D1 | ENSP00000340761 | ENSP00000360829 | BRI3-binding protein; Involved in tumorigenesis and may function by stabilizing p53/TP53 | Glycosyltransferase 6 domain containing 1 | 0.652 |
CCDC57 | BRI3BP | ENSP00000374292 | ENSP00000340761 | Coiled-coil domain containing 57 | BRI3-binding protein; Involved in tumorigenesis and may function by stabilizing p53/TP53 | 0.706 |
CCDC57 | GLT6D1 | ENSP00000374292 | ENSP00000360829 | Coiled-coil domain containing 57 | Glycosyltransferase 6 domain containing 1 | 0.691 |
DAB2IP | FAM83E | ENSP00000259371 | ENSP00000263266 | Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] | Protein FAM83E; May play a role in MAPK signaling | 0.600 |
DAB2IP | FUT1 | ENSP00000259371 | ENSP00000312021 | Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway; Blood group antigens | 0.636 |
DAB2IP | GLT6D1 | ENSP00000259371 | ENSP00000360829 | Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] | Glycosyltransferase 6 domain containing 1 | 0.679 |
DAB2IP | GTF3C5 | ENSP00000259371 | ENSP00000361180 | Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] | General transcription factor 3C polypeptide 5; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters; General transcription factors | 0.641 |
DAB2IP | TTLL11 | ENSP00000259371 | ENSP00000321346 | Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] | Tubulin polyglutamylase TTLL11; Polyglutamase which preferentially modifies alpha- tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Generates long side-chains (By similarity); Belongs to the tubulin--tyrosine ligase family | 0.518 |
DAB2IP | ZNF362 | ENSP00000259371 | ENSP00000446335 | Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] | Zinc finger protein 362; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.586 |
DAB2IP | ZSCAN20 | ENSP00000259371 | ENSP00000355053 | Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] | Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Myb/SANT domain containing | 0.496 |
FAM69B | GLT6D1 | ENSP00000360757 | ENSP00000360829 | Protein FAM69B; Family with sequence similarity 69 member B; Belongs to the FAM69 family | Glycosyltransferase 6 domain containing 1 | 0.812 |
FAM83E | DAB2IP | ENSP00000263266 | ENSP00000259371 | Protein FAM83E; May play a role in MAPK signaling | Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] | 0.600 |
FAM83E | FUT1 | ENSP00000263266 | ENSP00000312021 | Protein FAM83E; May play a role in MAPK signaling | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway; Blood group antigens | 0.624 |
FAM83E | GLT6D1 | ENSP00000263266 | ENSP00000360829 | Protein FAM83E; May play a role in MAPK signaling | Glycosyltransferase 6 domain containing 1 | 0.679 |
FAM83E | GTF3C5 | ENSP00000263266 | ENSP00000361180 | Protein FAM83E; May play a role in MAPK signaling | General transcription factor 3C polypeptide 5; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters; General transcription factors | 0.694 |
FAM83E | TTLL11 | ENSP00000263266 | ENSP00000321346 | Protein FAM83E; May play a role in MAPK signaling | Tubulin polyglutamylase TTLL11; Polyglutamase which preferentially modifies alpha- tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Generates long side-chains (By similarity); Belongs to the tubulin--tyrosine ligase family | 0.581 |
FAM83E | ZNF362 | ENSP00000263266 | ENSP00000446335 | Protein FAM83E; May play a role in MAPK signaling | Zinc finger protein 362; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.687 |
FAM83E | ZSCAN20 | ENSP00000263266 | ENSP00000355053 | Protein FAM83E; May play a role in MAPK signaling | Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Myb/SANT domain containing | 0.725 |
FUT1 | DAB2IP | ENSP00000312021 | ENSP00000259371 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway; Blood group antigens | Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon [...] | 0.636 |