COA7 protein (human) - STRING database

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COA7

Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV (231 aa)

Predicted Functional Partners:

WDHD1

0.830

SVIL

0.819

VMA21

0.815

SELENBP1

0.811

SCAF4

0.810

COA6

0.727

FKBP10

0.672

CEBPZOS

0.669

CCDC127

0.639

NDUFAF7

0.596

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC127	CEBPZOS	ENSP00000296824	ENSP00000384331	Coiled-coil domain containing 127	Protein CEBPZOS; CEBPZ opposite strand	0.701
CCDC127	COA7	ENSP00000296824	ENSP00000360593	Coiled-coil domain containing 127	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	0.639
CCDC127	FKBP10	ENSP00000296824	ENSP00000317232	Coiled-coil domain containing 127	Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis; EF-hand domain containing	0.420
CEBPZOS	CCDC127	ENSP00000384331	ENSP00000296824	Protein CEBPZOS; CEBPZ opposite strand	Coiled-coil domain containing 127	0.701
CEBPZOS	COA7	ENSP00000384331	ENSP00000360593	Protein CEBPZOS; CEBPZ opposite strand	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	0.669
CEBPZOS	FKBP10	ENSP00000384331	ENSP00000317232	Protein CEBPZOS; CEBPZ opposite strand	Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis; EF-hand domain containing	0.445
COA6	COA7	ENSP00000355572	ENSP00000360593	Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...]	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	0.727
COA7	CCDC127	ENSP00000360593	ENSP00000296824	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	Coiled-coil domain containing 127	0.639
COA7	CEBPZOS	ENSP00000360593	ENSP00000384331	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	Protein CEBPZOS; CEBPZ opposite strand	0.669
COA7	COA6	ENSP00000360593	ENSP00000355572	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomp [...]	0.727
COA7	FKBP10	ENSP00000360593	ENSP00000317232	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis; EF-hand domain containing	0.672
COA7	NDUFAF7	ENSP00000360593	ENSP00000002125	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	Protein arginine methyltransferase NDUFAF7, mitochondrial; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of ’Arg-118’ of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex; Belongs to the NDUFAF7 family	0.596
COA7	SCAF4	ENSP00000360593	ENSP00000286835	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	Splicing factor, arginine/serine-rich 15; May act to physically and functionally link transcription and pre-mRNA processing; Belongs to the splicing factor SR family	0.810
COA7	SELENBP1	ENSP00000360593	ENSP00000397261	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	Selenium-binding protein 1; Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity)	0.811
COA7	SVIL	ENSP00000360593	ENSP00000348128	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	Supervillin; Isoform 1- Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function; Belongs to the villin/gelsolin family	0.819
COA7	VMA21	ENSP00000360593	ENSP00000333255	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum	0.815
COA7	WDHD1	ENSP00000360593	ENSP00000353793	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	WD repeat and HMG-box DNA-binding protein 1; Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication; WD repeat domain containing	0.830
FKBP10	CCDC127	ENSP00000317232	ENSP00000296824	Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis; EF-hand domain containing	Coiled-coil domain containing 127	0.420
FKBP10	CEBPZOS	ENSP00000317232	ENSP00000384331	Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis; EF-hand domain containing	Protein CEBPZOS; CEBPZ opposite strand	0.445
FKBP10	COA7	ENSP00000317232	ENSP00000360593	Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis; EF-hand domain containing	Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV	0.672

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