node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC135 | CCDC65 | ENSP00000353942 | ENSP00000312706 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Coiled-coil domain-containing protein 65; May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein regulatory complex; Belongs to the CCDC65 family | 0.589 |
CCDC135 | GAS8 | ENSP00000353942 | ENSP00000268699 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | 0.719 |
CCDC135 | IQCA1 | ENSP00000353942 | ENSP00000407213 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | IQ motif containing with AAA domain 1 | 0.702 |
CCDC135 | TCTE1 | ENSP00000353942 | ENSP00000360560 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.680 |
CCDC65 | CCDC135 | ENSP00000312706 | ENSP00000353942 | Coiled-coil domain-containing protein 65; May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein regulatory complex; Belongs to the CCDC65 family | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | 0.589 |
CCDC65 | GAS8 | ENSP00000312706 | ENSP00000268699 | Coiled-coil domain-containing protein 65; May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein regulatory complex; Belongs to the CCDC65 family | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | 0.881 |
CCDC65 | IQCA1 | ENSP00000312706 | ENSP00000407213 | Coiled-coil domain-containing protein 65; May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein regulatory complex; Belongs to the CCDC65 family | IQ motif containing with AAA domain 1 | 0.663 |
CCDC65 | TCTE1 | ENSP00000312706 | ENSP00000360560 | Coiled-coil domain-containing protein 65; May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein regulatory complex; Belongs to the CCDC65 family | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.676 |
GAS8 | CCDC135 | ENSP00000268699 | ENSP00000353942 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | 0.719 |
GAS8 | CCDC65 | ENSP00000268699 | ENSP00000312706 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | Coiled-coil domain-containing protein 65; May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein regulatory complex; Belongs to the CCDC65 family | 0.881 |
GAS8 | IQCA1 | ENSP00000268699 | ENSP00000407213 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | IQ motif containing with AAA domain 1 | 0.664 |
GAS8 | TCTE1 | ENSP00000268699 | ENSP00000360560 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.677 |
IQCA1 | CCDC135 | ENSP00000407213 | ENSP00000353942 | IQ motif containing with AAA domain 1 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | 0.702 |
IQCA1 | CCDC65 | ENSP00000407213 | ENSP00000312706 | IQ motif containing with AAA domain 1 | Coiled-coil domain-containing protein 65; May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein regulatory complex; Belongs to the CCDC65 family | 0.663 |
IQCA1 | GAS8 | ENSP00000407213 | ENSP00000268699 | IQ motif containing with AAA domain 1 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | 0.664 |
IQCA1 | TCTE1 | ENSP00000407213 | ENSP00000360560 | IQ motif containing with AAA domain 1 | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.717 |
LPHN1 | TCTE1 | ENSP00000340688 | ENSP00000360560 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.685 |
LPHN2 | TCTE1 | ENSP00000322270 | ENSP00000360560 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.685 |
LPHN3 | TCTE1 | ENSP00000422533 | ENSP00000360560 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.685 |
MED6 | TCTE1 | ENSP00000481920 | ENSP00000360560 | Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.706 |