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  • 11.0 [archived version]
STRINGSTRING
KIAA1751 KIAA1751 ACTRT2 ACTRT2 TSACC TSACC ANKRD7 ANKRD7 C22orf23 C22orf23 RIMBP3C RIMBP3C ALS2CR11 ALS2CR11 SLC25A51 SLC25A51 RIMBP3B RIMBP3B DMRTB1 DMRTB1 LMCD1 LMCD1
"DMRTB1" - Doublesex- and mab-3-related transcription factor B1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
DMRTB1Doublesex- and mab-3-related transcription factor B1; DMRT like family B with proline rich C-terminal 1; Belongs to the DMRT family (342 aa)    
Predicted Functional Partners:
TSACC
TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family (125 aa)
            
  0.543
RIMBP3C
RIMS binding protein 3C; Belongs to the RIMBP family (1639 aa)
      
   
  0.541
RIMBP3B
RIMS binding protein 3B (1639 aa)
      
   
  0.521
ALS2CR11
C2 calcium-dependent domain-containing protein 6; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 (1820 aa)
      
   
  0.509
C22orf23
UPF0193 protein EVG1; Chromosome 22 open reading frame 23 (217 aa)
      
   
  0.501
LMCD1
LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway; LIM domain containing (365 aa)
            
  0.500
SLC25A51
Solute carrier family 25 member 51 (297 aa)
            
  0.488
KIAA1751
Cilia- and flagella-associated protein 74; As part of the central apparatus of the cilium axoneme may play a role in cilium movement (1584 aa)
      
   
  0.483
ANKRD7
Ankyrin repeat domain-containing protein 7; Ankyrin repeat domain containing (254 aa)
        
 
  0.480
ACTRT2
Actin related protein T2 (377 aa)
        
 
  0.474
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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