• Version:
  • 11.0 [archived version]
STRINGSTRING
MRPL34 MRPL34 MRPS2 MRPS2 MRPL40 MRPL40 MRPL37 MRPL37 MRPL41 MRPL41 MRPL47 MRPL47 MRPL27 MRPL27 MRPL32 MRPL32 MRPL13 MRPL13 MRPL17 MRPL17 MRPL4 MRPL4
"MRPL41" - 39S ribosomal protein L41, mitochondrial in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRPL4139S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (137 aa)    
Predicted Functional Partners:
MRPL47
Mitochondrial ribosomal protein L47 (250 aa)
     
  0.999
MRPL13
Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family (178 aa)
     
  0.999
MRPL17
Mitochondrial ribosomal protein L17 (175 aa)
     
    0.999
MRPL40
Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family (206 aa)
     
    0.999
MRPL27
Mitochondrial ribosomal protein L27 (148 aa)
     
    0.999
MRPL32
Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family (188 aa)
     
    0.999
MRPL34
Mitochondrial ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family (92 aa)
     
  0.999
MRPL37
Mitochondrial ribosomal protein L37; Belongs to the mitochondrion-specific ribosomal protein mL37 family (423 aa)
     
  0.999
MRPL4
Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family (311 aa)
     
    0.999
MRPS2
Mitochondrial ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family (296 aa)
     
  0.998
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]