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  • 11.0 [archived version]
STRINGSTRING
TPRX1 TPRX1 ARGFX ARGFX LEUTX LEUTX LBX1 LBX1 UNC5C UNC5C RHOXF2 RHOXF2 TGIF2LX TGIF2LX ARMCX2 ARMCX2 TNP1 TNP1 USP26 USP26 ODF4 ODF4
"RHOXF2" - Rhox homeobox family member 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
RHOXF2Rhox homeobox family member 2; Transcription factor maybe involved in reproductive processes. Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis; PRD class homeoboxes and pseudogenes (288 aa)    
Predicted Functional Partners:
ARMCX2
Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells; Armadillo repeat containing (632 aa)
       
      0.723
UNC5C
Netrin receptor UNC5C; Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand; Belongs to the unc-5 family (931 aa)
           
  0.708
TGIF2LX
Homeobox protein TGIF2LX; May have a transcription role in testis; TALE class homeoboxes and pseudogenes (241 aa)
       
 
  0.685
TPRX1
Tetra-peptide repeat homeobox protein 1; PRD class homeoboxes and pseudogenes (411 aa)
       
 
  0.603
TNP1
Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction; Belongs to the nuclear transition protein 1 family (55 aa)
           
  0.588
ODF4
Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton (257 aa)
           
  0.568
LEUTX
PRD class homeoboxes and pseudogenes (168 aa)
       
 
  0.567
ARGFX
Arginine-fifty homeobox; Putative transcription factor; PRD class homeoboxes and pseudogenes (315 aa)
       
 
  0.547
LBX1
Transcription factor LBX1; Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord; NKL subclass homeoboxes and pseudogenes (281 aa)
     
 
  0.546
USP26
Ubiquitin carboxyl-terminal hydrolase 26; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity). Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway; Belongs to the peptidase C19 family (913 aa)
           
  0.544
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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