node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRF2 | FAM210B | ENSP00000220659 | ENSP00000360437 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | 0.441 |
FAM177A1 | FAM210B | ENSP00000280987 | ENSP00000360437 | Protein FAM177A1; Family with sequence similarity 177 member A1 | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | 0.422 |
FAM177A1 | TBC1D8B | ENSP00000280987 | ENSP00000349781 | Protein FAM177A1; Family with sequence similarity 177 member A1 | TBC1 domain family member 8B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing | 0.444 |
FAM177A1 | TIMMDC1 | ENSP00000280987 | ENSP00000418803 | Protein FAM177A1; Family with sequence similarity 177 member A1 | Complex I assembly factor TIMMDC1, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I | 0.438 |
FAM209A | FAM210B | ENSP00000360379 | ENSP00000360437 | Protein FAM209A; Family with sequence similarity 209 member A | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | 0.535 |
FAM210B | BRF2 | ENSP00000360437 | ENSP00000220659 | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family | 0.441 |
FAM210B | FAM177A1 | ENSP00000360437 | ENSP00000280987 | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | Protein FAM177A1; Family with sequence similarity 177 member A1 | 0.422 |
FAM210B | FAM209A | ENSP00000360437 | ENSP00000360379 | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | Protein FAM209A; Family with sequence similarity 209 member A | 0.535 |
FAM210B | SLMO2 | ENSP00000360437 | ENSP00000348206 | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | PRELI domain containing protein 3B; Slowmo homolog 2 (Drosophila) | 0.454 |
FAM210B | TBC1D8B | ENSP00000360437 | ENSP00000349781 | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | TBC1 domain family member 8B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing | 0.405 |
FAM210B | TIMMDC1 | ENSP00000360437 | ENSP00000418803 | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | Complex I assembly factor TIMMDC1, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I | 0.402 |
SLMO2 | FAM210B | ENSP00000348206 | ENSP00000360437 | PRELI domain containing protein 3B; Slowmo homolog 2 (Drosophila) | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | 0.454 |
TBC1D8B | FAM177A1 | ENSP00000349781 | ENSP00000280987 | TBC1 domain family member 8B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing | Protein FAM177A1; Family with sequence similarity 177 member A1 | 0.444 |
TBC1D8B | FAM210B | ENSP00000349781 | ENSP00000360437 | TBC1 domain family member 8B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | 0.405 |
TBC1D8B | TIMMDC1 | ENSP00000349781 | ENSP00000418803 | TBC1 domain family member 8B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing | Complex I assembly factor TIMMDC1, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I | 0.422 |
TIMMDC1 | FAM177A1 | ENSP00000418803 | ENSP00000280987 | Complex I assembly factor TIMMDC1, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I | Protein FAM177A1; Family with sequence similarity 177 member A1 | 0.438 |
TIMMDC1 | FAM210B | ENSP00000418803 | ENSP00000360437 | Complex I assembly factor TIMMDC1, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner; Belongs to the FAM210 family | 0.402 |
TIMMDC1 | TBC1D8B | ENSP00000418803 | ENSP00000349781 | Complex I assembly factor TIMMDC1, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I | TBC1 domain family member 8B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing | 0.422 |