GPR110 protein (human) - STRING database

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GPR110

Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily (910 aa)

Predicted Functional Partners:

GPR141

0.721

GPR139

0.716

PTGER1

0.682

GPR148

0.672

SSTR4

0.653

GPR123

0.645

PPRC1

0.560

TTC16

0.559

GPR124

0.543

GPR135

0.541

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPR110	GPR123	ENSP00000360299	ENSP00000376384	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Adhesion G protein-coupled receptor A1; Orphan receptor	0.645
GPR110	GPR124	ENSP00000360299	ENSP00000406367	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Adhesion G protein-coupled receptor A2; Endothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity). Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity). Has a major role in establishing the blood-brain barrier (By similarity). Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	0.543
GPR110	GPR135	ENSP00000360299	ENSP00000378548	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	0.541
GPR110	GPR139	ENSP00000360299	ENSP00000458791	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; G protein-coupled receptors, Class A orphans	0.716
GPR110	GPR141	ENSP00000360299	ENSP00000390410	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Probable G-protein coupled receptor 141; Orphan receptor; G protein-coupled receptors, Class A orphans	0.721
GPR110	GPR148	ENSP00000360299	ENSP00000308908	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Probable G-protein coupled receptor 148; Orphan receptor; G protein-coupled receptors, Class A orphans	0.672
GPR110	PPRC1	ENSP00000360299	ENSP00000278070	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1; Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes; RNA binding motif containing	0.560
GPR110	PTGER1	ENSP00000360299	ENSP00000292513	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Prostaglandin E2 receptor EP1 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues; Belongs to the G-protein coupled receptor 1 family	0.682
GPR110	SSTR4	ENSP00000360299	ENSP00000255008	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Somatostatin receptor type 4; Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells	0.653
GPR110	TTC16	ENSP00000360299	ENSP00000362386	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Tetratricopeptide repeat domain containing	0.559
GPR123	GPR110	ENSP00000376384	ENSP00000360299	Adhesion G protein-coupled receptor A1; Orphan receptor	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	0.645
GPR124	GPR110	ENSP00000406367	ENSP00000360299	Adhesion G protein-coupled receptor A2; Endothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity). Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity). Has a major role in establishing the blood-brain barrier (By similarity). Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	0.543
GPR135	GPR110	ENSP00000378548	ENSP00000360299	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	0.541
GPR135	GPR139	ENSP00000378548	ENSP00000458791	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; G protein-coupled receptors, Class A orphans	0.489
GPR135	GPR141	ENSP00000378548	ENSP00000390410	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 141; Orphan receptor; G protein-coupled receptors, Class A orphans	0.668
GPR139	GPR110	ENSP00000458791	ENSP00000360299	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; G protein-coupled receptors, Class A orphans	Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	0.716
GPR139	GPR135	ENSP00000458791	ENSP00000378548	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	0.489
GPR139	GPR141	ENSP00000458791	ENSP00000390410	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 141; Orphan receptor; G protein-coupled receptors, Class A orphans	0.759
GPR139	GPR148	ENSP00000458791	ENSP00000308908	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 148; Orphan receptor; G protein-coupled receptors, Class A orphans	0.737
GPR139	PPRC1	ENSP00000458791	ENSP00000278070	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; G protein-coupled receptors, Class A orphans	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1; Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes; RNA binding motif containing	0.484

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